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Basis of Presentation and Summary of Significant Accounting Policies - Revenue by Source (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Disaggregation of Revenue [Line Items]        
Total revenue $ 90,043 $ 27,995 $ 146,200 $ 57,264
Material Sales: Captisol        
Disaggregation of Revenue [Line Items]        
Total revenue 7,612 5,550 12,003 6,672
License fees, milestones and other        
Disaggregation of Revenue [Line Items]        
Total revenue 51,035 8,234 81,981 12,151
License Fees        
Disaggregation of Revenue [Line Items]        
Total revenue 47,981 666 74,936 3,538
Milestone        
Disaggregation of Revenue [Line Items]        
Total revenue 1,919 4,497 4,744 5,505
Other        
Disaggregation of Revenue [Line Items]        
Total revenue $ 1,135 $ 3,071 $ 2,301 $ 3,108