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Business Combinations - Assets Acquired and Liabilities Assumed (Details) - USD ($) $ in Thousands | Dec. 31, 2018 | Oct. 31, 2018 | Dec. 31, 2017 | Oct. 06, 2017 | Jan. 08, 2016
--- | --- | --- | --- | --- | ---
Business Acquisition [Line Items] |  |  |  |  |
Goodwill | $ 86,646 |  | $ 85,959 |  |
Vernalis |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Cash and cash equivalents |  | $ 34,286 |  |  |
Restricted cash |  | 2,836 |  |  |
Other assets |  | 6,383 |  |  |
Accounts payable and accrued liabilities |  | (3,403) |  |  |
Restructuring and product reserves |  | (7,118) |  |  |
Deferred revenue |  | (746) |  |  |
Intangible asset with finite life - core technology |  | 7,000 |  |  |
Goodwill |  | 3,740 |  |  |
Total consideration |  | $ 42,978 |  |  |
Crystal |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Cash and cash equivalents |  |  |  | $ 224 |
Accounts receivable |  |  |  | 2,513 |
Prepaid expenses and other current assets |  |  |  | 201 |
Property and equipment, net |  |  |  | 589 |
Current liabilities assumed |  |  |  | (354) |
Deferred revenue |  |  |  | (4,624) |
Deferred tax liabilities, net |  |  |  | (9,503) |
Intangible asset with finite life - core technology |  |  |  | 36,000 |
Liabilities assumed |  |  |  | (129) |
Goodwill |  |  |  | 10,697 |
Total consideration |  |  |  | $ 35,743 |
OMT |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Cash and cash equivalents |  |  |  |  | $ 3,504
Accounts receivable |  |  |  |  | 5
Income tax receivable |  |  |  |  | 136
Prepaid expenses and other current assets |  |  |  |  | 1
Deferred tax liabilities, net |  |  |  |  | (55,708)
Intangible asset with finite life - core technology |  |  |  |  | 167,000
Liabilities assumed |  |  |  |  | (1,528)
Goodwill |  |  |  |  | 59,969
Total consideration |  |  |  |  | $ 173,379

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