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Balance Sheet Account Details - Contingent Liabilities (Details) - USD ($) | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017
Business Acquisition [Line Items] |  |
Revenue royalty payable on all Cydex-related revenue (as a percent) |  | 20.00%
Cydex-related revenue amount that triggers royalty payments |  | $ 15,000,000.0
Additional revenue royalty payable when higher threshold of Cydex-related revenue met (percent) |  | 10.00%
Cydex-related revenue amount that triggers additional royalty payments |  | $ 35,000,000.0
Contingent Liability [Roll Forward] |  |
Commercial rights at beginning of period | $ 14,000,000 | 8,100,000
Payments | (4,925,000) | (5,000,000)
Fair Value Adjustment | 3,426,000 | 2,500,000
Additions |  | 8,400,000
Commercial rights at end of period | 12,501,000 | 14,000,000
Cydex |  |
Contingent Liability [Roll Forward] |  |
Commercial rights at beginning of period | 1,600,000 | 6,600,000
Payments | (25,000) | (5,000,000)
Fair Value Adjustment | (1,050,000) | 0
Additions |  | 0
Commercial rights at end of period | 525,000 | 1,600,000
Metabasis |  |
Contingent Liability [Roll Forward] |  |
Commercial rights at beginning of period | 4,000,000 | 1,500,000
Payments | (3,900,000) | 0
Fair Value Adjustment | 5,400,000 | 2,500,000
Additions |  | 0
Commercial rights at end of period | 5,500,000 | 4,000,000
Crystal |  |
Contingent Liability [Roll Forward] |  |
Commercial rights at beginning of period | 8,400,000 | 0
Payments | (1,000,000) | 0
Fair Value Adjustment | (924,000) | 0
Additions |  | 8,400,000
Commercial rights at end of period | $ 6,476,000 | $ 8,400,000

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