    <SEC-DOCUMENT>0000886163-19-000043-index.html : 20190305
    <SEC-HEADER>0000886163-19-000043.hdr.sgml : 20190305
    <ACCEPTANCE-DATETIME>20190305171642
    ACCESSION NUMBER:		0000886163-19-000043
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		28
    CONFORMED PERIOD OF REPORT:	20190305
    ITEM INFORMATION:		Entry into a Material Definitive Agreement
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20190305
    DATE AS OF CHANGE:		20190305

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			LIGAND PHARMACEUTICALS INC
    		CENTRAL INDEX KEY:			0000886163
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				770160744
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33093
    		FILM NUMBER:		19659586

    	BUSINESS ADDRESS:
    		STREET 1:		3911 SORRENTO VALLEY BLVD
    		STREET 2:		SUITE 110
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		858-550-7500

    	MAIL ADDRESS:
    		STREET 1:		3911 SORRENTO VALLEY BLVD
    		STREET 2:		SUITE 110
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>ligand-8xk_030519.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: ligand-8xk_030519.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-2.1
    <SEQUENCE>2
    <FILENAME>ex218k3519.htm
    <DESCRIPTION>EXHIBIT 2.1
    <TEXT>
    Document 2 - file: ex218k3519.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>3
    <FILENAME>exhibit991investorslides.htm
    <DESCRIPTION>EXHIBIT 99.1
    <TEXT>
    Document 3 - file: exhibit991investorslides.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>exhibit991investorslides001.jpg
    <TEXT>
    Document 4 - file: exhibit991investorslides001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>exhibit991investorslides002.jpg
    <TEXT>
    Document 5 - file: exhibit991investorslides002.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>exhibit991investorslides003.jpg
    <TEXT>
    Document 6 - file: exhibit991investorslides003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>exhibit991investorslides004.jpg
    <TEXT>
    Document 7 - file: exhibit991investorslides004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>exhibit991investorslides005.jpg
    <TEXT>
    Document 8 - file: exhibit991investorslides005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>exhibit991investorslides006.jpg
    <TEXT>
    Document 9 - file: exhibit991investorslides006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>exhibit991investorslides007.jpg
    <TEXT>
    Document 10 - file: exhibit991investorslides007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>exhibit991investorslides008.jpg
    <TEXT>
    Document 11 - file: exhibit991investorslides008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>exhibit991investorslides009.jpg
    <TEXT>
    Document 12 - file: exhibit991investorslides009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>exhibit991investorslides010.jpg
    <TEXT>
    Document 13 - file: exhibit991investorslides010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>exhibit991investorslides011.jpg
    <TEXT>
    Document 14 - file: exhibit991investorslides011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>exhibit991investorslides012.jpg
    <TEXT>
    Document 15 - file: exhibit991investorslides012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>exhibit991investorslides013.jpg
    <TEXT>
    Document 16 - file: exhibit991investorslides013.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>exhibit991investorslides014.jpg
    <TEXT>
    Document 17 - file: exhibit991investorslides014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>exhibit991investorslides015.jpg
    <TEXT>
    Document 18 - file: exhibit991investorslides015.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>exhibit991investorslides016.jpg
    <TEXT>
    Document 19 - file: exhibit991investorslides016.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>exhibit991investorslides017.jpg
    <TEXT>
    Document 20 - file: exhibit991investorslides017.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>exhibit991investorslides018.jpg
    <TEXT>
    Document 21 - file: exhibit991investorslides018.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>exhibit991investorslides019.jpg
    <TEXT>
    Document 22 - file: exhibit991investorslides019.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>exhibit991investorslides020.jpg
    <TEXT>
    Document 23 - file: exhibit991investorslides020.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>exhibit991investorslides021.jpg
    <TEXT>
    Document 24 - file: exhibit991investorslides021.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>exhibit991investorslides022.jpg
    <TEXT>
    Document 25 - file: exhibit991investorslides022.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>exhibit991investorslides023.jpg
    <TEXT>
    Document 26 - file: exhibit991investorslides023.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>exhibit991investorslides024.jpg
    <TEXT>
    Document 27 - file: exhibit991investorslides024.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>exhibit991investorslides025.jpg
    <TEXT>
    Document 28 - file: exhibit991investorslides025.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>