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Business Combinations - Narrative (Details) |  |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Jul. 23, 2019 USD ($) | Oct. 06, 2017 USD ($) numberOfCollaborationAgreements | Oct. 31, 2018 USD ($) | Dec. 31, 2019 USD ($) | Dec. 31, 2018 USD ($)
Business Acquisition [Line Items] |  |  |  |  |
Finite-lived intangible asset, useful life |  |  |  | 20 years |
Goodwill |  |  |  | $ 95,229,000 | $ 86,646,000
Ab Initio |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Consideration transferred | $ 12,000,000.0 |  |  |  |
Gross payments to acquire business | 11,840,000 |  |  |  |
Cash holdback for potential indemnification claims | $ 150,000 |  |  |  |
Projected cash flow discount rate (as a percent) | 12.00% |  |  |  |
Goodwill | $ 6,275,000 |  |  |  |
Vernalis |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Gross payments to acquire business |  |  | $ 43,000,000.0 |  |
Projected cash flow discount rate (as a percent) |  |  | 34.00% |  |
Goodwill |  |  | $ 5,939,000 |  |
Crystal |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Gross payments to acquire business |  | $ 27,200,000 |  |  |
Working capital adjustment |  | 2,200,000 |  |  |
Total share consideration |  | 10,500,000 |  |  |
Cash payable to Crystal Shareholders |  | 336,000 |  | $ 20,000.00 |
Fair value of contingent consideration |  | 8,401,000 |  |  |
Goodwill |  | $ 10,697,000 |  |  |
Core Technology | Ab Initio |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Finite-lived intangible asset, useful life | 20 years |  |  |  |
Core Technology | Vernalis |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Finite-lived intangible asset, useful life |  |  | 9 years |  |
Core Technology | Crystal |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Projected cash flow discount rate (as a percent) |  | 10.80% |  |  |
Finite-lived intangible asset, useful life |  | 20 years |  |  |
Average cash flow discount rate (as a percent) |  | 4.60% |  |  |
Threshold of Revenues above $15 million with Three Collaboration Agreements | Crystal |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Revenue royalty payable on all Cydex-related revenue (as a percent) |  | 10.00% |  |  |
Cydex-related revenue amount that triggers royalty payments |  | $ 15,000,000 |  |  |
Threshold of Revenues above $1.5 million with Four Collaboration Agreements | Crystal |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Revenue royalty payable on all Cydex-related revenue (as a percent) |  | 20.00% |  |  |
Cydex-related revenue amount that triggers royalty payments |  | $ 1,500,000 |  |  |
Number of collaboration agreements | numberOfCollaborationAgreements |  | 4 |  |  |

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