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Basis of Presentation and Summary of Significant Accounting Policies - Accounting for Share-Based Compensation (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2020 | Sep. 30, 2019 | Sep. 30, 2020 | Sep. 30, 2019
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense | $ 7,740 | $ 6,297 | $ 20,752 | $ 18,215
SBC - Research and development expenses |  |  |  |
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense | 3,094 | 2,481 | 8,510 | 7,136
SBC - General and administrative expenses |  |  |  |
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense | $ 4,646 | $ 3,816 | $ 12,242 | $ 11,079

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