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Basis of Presentation and Summary of Significant Accounting Policies - Accounting for Share-Based Compensation (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2021 | Jun. 30, 2020 | Jun. 30, 2021 | Jun. 30, 2020
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense | $ 10,216 | $ 7,359 | $ 18,621 | $ 13,012
SBC - Research and development expenses |  |  |  |
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense | 4,556 | 3,019 | 8,495 | 5,416
SBC - General and administrative expenses |  |  |  |
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense | $ 5,660 | $ 4,340 | $ 10,126 | $ 7,596

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