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Fair Value Measurements - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) | 1 Months Ended | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Jan. 31, 2010 contingent_value_right contingent_value_right_series | Jun. 30, 2021 USD ($) | Jun. 30, 2021 USD ($) | Dec. 31, 2020 USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Number of CVR Series | contingent_value_right_series | 4 |  |  |
Transferred over Time | Phase 3 Clinical Trial |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Gross contract asset |  | $ 10,000,000 | $ 10,000,000 |
Maximum | Transferred over Time | Development, Regulatory, & Commercial Milestones and Tiered Royalties |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Investments |  | 375,000,000 | 375,000,000 |
Metabasis |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Number of CVRs issued per acquiree share | contingent_value_right | 4 |  |  |
Number of CVRs issued from each CVR series | contingent_value_right | 1 |  |  |
Frequency of cash payments to CVR holders | 6 months |  |  |
Contingent liabilities - Icagen |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Payment for contingent consideration liabilities |  |  | 1,100,000 |
Contingent liabilities - Pfenex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Reduction in contingent liability |  | 34,100,000 | 33,800,000 |
Recurring |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 279,972,000 | 279,972,000 | $ 363,567,000
Liabilities, fair value |  | 14,802,000 | 14,802,000 | 49,193,000
Recurring | Contingent liabilities - Crystal |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 800,000 | 800,000 | 800,000
Recurring | Contingent liabilities - CyDex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 376,000 | 376,000 | 508,000
Recurring | Contingent liabilities - Metabasis |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 3,930,000 | 3,930,000 | 3,821,000
Recurring | Contingent liabilities - Icagen |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 5,625,000 | 5,625,000 | 6,404,000
Recurring | Contingent liabilities - Pfenex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 3,800,000 | 3,800,000 | 37,600,000
Recurring | Contingent liabilities - xCella |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 240,000 | 240,000 | 0
Recurring | Amounts owed to former licensor |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 31,000 | 31,000 | 60,000
Recurring | Short-term investments |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 239,749,000 | 239,749,000 | 324,478,000
Recurring | Investment in Viking common stock |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 40,223,000 | 40,223,000 | 32,763,000
Recurring | Investment in warrants |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 0 | 0 | 6,326,000
Recurring | Level 1 |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 45,892,000 | 45,892,000 | 42,527,000
Liabilities, fair value |  | 31,000 | 31,000 | 60,000
Recurring | Level 1 | Contingent liabilities - Crystal |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 1 | Contingent liabilities - CyDex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 1 | Contingent liabilities - Metabasis |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 1 | Contingent liabilities - Icagen |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 1 | Contingent liabilities - Pfenex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 1 | Contingent liabilities - xCella |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 1 | Amounts owed to former licensor |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 31,000 | 31,000 | 60,000
Recurring | Level 1 | Short-term investments |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 5,669,000 | 5,669,000 | 3,438,000
Recurring | Level 1 | Investment in Viking common stock |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 40,223,000 | 40,223,000 | 32,763,000
Recurring | Level 1 | Investment in warrants |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 0 | 0 | 6,326,000
Recurring | Level 2 |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 233,368,000 | 233,368,000 | 320,647,000
Liabilities, fair value |  | 3,930,000 | 3,930,000 | 3,821,000
Recurring | Level 2 | Contingent liabilities - Crystal |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 2 | Contingent liabilities - CyDex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 2 | Contingent liabilities - Metabasis |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 3,930,000 | 3,930,000 | 3,821,000
Recurring | Level 2 | Contingent liabilities - Icagen |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 2 | Contingent liabilities - Pfenex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 2 | Contingent liabilities - xCella |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 2 | Amounts owed to former licensor |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 2 | Short-term investments |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 233,368,000 | 233,368,000 | 320,647,000
Recurring | Level 2 | Investment in Viking common stock |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 0 | 0 | 0
Recurring | Level 2 | Investment in warrants |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 0 | 0 | 0
Recurring | Level 3 |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 712,000 | 712,000 | 393,000
Liabilities, fair value |  | 10,841,000 | 10,841,000 | 45,312,000
Recurring | Level 3 | Contingent liabilities - Crystal |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 800,000 | 800,000 | 800,000
Recurring | Level 3 | Contingent liabilities - CyDex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 376,000 | 376,000 | 508,000
Recurring | Level 3 | Contingent liabilities - Metabasis |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 3 | Contingent liabilities - Icagen |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 5,625,000 | 5,625,000 | 6,404,000
Recurring | Level 3 | Contingent liabilities - Pfenex |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 3,800,000 | 3,800,000 | 37,600,000
Recurring | Level 3 | Contingent liabilities - xCella |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 240,000 | 240,000 | 0
Recurring | Level 3 | Amounts owed to former licensor |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Liabilities, fair value |  | 0 | 0 | 0
Recurring | Level 3 | Short-term investments |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 712,000 | 712,000 | 393,000
Recurring | Level 3 | Investment in Viking common stock |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | 0 | 0 | 0
Recurring | Level 3 | Investment in warrants |  |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |  |
Assets, fair value |  | $ 0 | $ 0 | $ 0

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