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Basis of Presentation and Summary of Significant Accounting Policies - Revenue by Source (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | $ 64,835 | $ 41,848 | $ 204,660 | $ 116,429
Royalties |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 15,648 | 9,005 | 31,376 | 22,751
Kyprolis |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 8,821 | 6,923 | 18,548 | 16,809
Evomela |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 2,665 | 1,802 | 7,191 | 4,577
Other |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 4,162 | 280 | 5,637 | 1,365
Captisol |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 35,093 | 23,389 | 128,875 | 68,966
Contract revenue |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 14,094 | 9,454 | 44,409 | 24,712
Service Revenue |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 4,828 | 7,341 | 17,650 | 15,280
License Fees |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 200 | 158 | 2,293 | 1,793
Milestone |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | 7,419 | 960 | 19,436 | 4,766
Other |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Total revenue | $ 1,647 | $ 995 | $ 5,030 | $ 2,873

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