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Convertible Senior Notes - Narrative (Details)				1 Months Ended						2 Months Ended			12 Months Ended
	Aug. 15, 2019 USD ($)	Dec. 31, 2018 USD ($)	May 22, 2018 USD ($) $ / shares shares	Feb. 28, 2022 USD ($)	Jan. 31, 2021 USD ($)	Apr. 30, 2020 USD ($)	Jun. 30, 2019 USD ($)	May 31, 2018 USD ($) trading_day shares	Aug. 31, 2014 USD ($) trading_day day $ / shares shares	Nov. 30, 2018 USD ($)	Aug. 31, 2018 USD ($)	Apr. 30, 2018 USD ($)	Dec. 31, 2021 USD ($) option shares	Dec. 31, 2020 USD ($) $ / shares	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)
Debt Instrument [Line Items]
Loss on debt extinguishment													$ 7,303,000	$ 2,466,000	$ 0
Warrants issued in public offering (shares) | shares									3,264,643
Exercise price of convertible bond hedge (USD per share) | $ / shares									$ 75.05
Warrant exercise price (USD per share) | $ / shares									$ 125.08					$ 1.50
Debt issuance costs related to the equity component of convertible debt													12,407,000	$ 3,236,000
Value of warrants issued													500,000
Payments to unwind warrants													18,400,000
Proceeds from unwinding convertible bond hedges													$ 18,900,000
Number of options under convertible bond hedges | option													598,021
Convertible Notes | 2019 Convertible Senior Notes
Debt Instrument [Line Items]
Face amount of debt instrument									$ 245,000,000
Net proceeds from debt issuance									$ 239,300,000
Effective rate (as a percent)									5.83%
Convertible debt conversion ratio									0.0133251
Debt conversion price per share (USD per share) | $ / shares									$ 75.05
Interest on debt instrument (as a percent)									0.75%
If-converted value in excess of principal		$ 23,400,000	$ 341,600,000
Increase (decrease) in if-converted value in excess of principal																$ 118,700,000
Notices for conversion							$ 1,000,000				$ 195,900,000	$ 21,800,000
Conversion value over the principal amount							$ 500,000			$ 439,600,000		$ 31,600,000
Loss on debt extinguishment															3,200,000
Repayments of notes	$ 26,300,000
Debt issuance costs related to the liability component of convertible debt	$ 11,900,000
Net change in fair value of derivatives															11,000,000
Gain (loss) on derivative liabilities															(11,000,000)
Convertible Notes | 2019 Convertible Senior Notes | Redemption Period One
Debt Instrument [Line Items]
Number of trading days | trading_day									20
Number of consecutive trading days | trading_day									30
Stock price trigger to classify convertible debt as current (as a percent)									130.00%
Convertible Notes | 2019 Convertible Senior Notes | Redemption Period Two
Debt Instrument [Line Items]
Number of trading days | day									5
Number of consecutive trading days | trading_day									10
Maximum threshold of debt trading price trigger (as a percent)									98.00%
Convertible Notes | 2023 Convertible Senior Notes
Debt Instrument [Line Items]
Face amount of debt instrument			$ 750,000,000										$ 343,301,000	495,280,000
Net proceeds from debt issuance								$ 733,100,000
Convertible debt conversion ratio								0.0040244
Debt conversion price per share (USD per share) | $ / shares			$ 248.48
Interest on debt instrument (as a percent)			0.75%
Loss on debt extinguishment													7,300,000	2,500,000
Repayments of notes					$ 19,100,000	$ 203,800,000							156,000,000	222,800,000
Debt issuance costs related to the liability component of convertible debt													$ 13,700,000
Warrants issued in public offering (shares) | shares			3,018,327					3,018,327					2,559,254
Warrant exercise price (USD per share) | $ / shares			$ 315.38
Debt issuance costs													$ 16,900,000
Repurchased amount of debt instrument					20,300,000	234,400,000							152,000,000	254,700,000
Accrued interest portion of repurchased amount of debt instrument					$ 100,000	$ 600,000							300,000	600,000
Reduction in debt discount													13,700,000	35,000,000
Debt issuance costs related to the equity component of convertible debt													$ 10,200,000	$ 3,200,000
Payments for convertible bond hedges			$ 140,300,000
Value of warrants issued			$ 90,000,000
Convertible Notes | 2023 Convertible Senior Notes | Subsequent Event
Debt Instrument [Line Items]
Repayments of notes				$ 123,900,000
Repurchased amount of debt instrument				125,500,000
Accrued interest portion of repurchased amount of debt instrument				$ 300,000
Convertible Notes | 2023 Convertible Senior Notes | Redemption Period One
Debt Instrument [Line Items]
Number of trading days | trading_day								20
Number of consecutive trading days | trading_day								30
Stock price trigger to classify convertible debt as current (as a percent)								130.00%
Convertible Notes | 2023 Convertible Senior Notes | Redemption Period Two
Debt Instrument [Line Items]
Number of trading days | trading_day								5
Number of consecutive trading days | trading_day								10
Maximum threshold of debt trading price trigger (as a percent)								98.00%
Other Expense | Convertible Notes | 2019 Convertible Senior Notes
Debt Instrument [Line Items]
Net change in fair value of derivatives															10,200,000
Gain (loss) on derivative liabilities															$ (10,200,000)

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