Exhibit 21.1

LIGAND PHARMACEUTICALS INCORPORATED

LIST OF SUBSIDIARIES

Name						Jurisdiction of Incorporation
Ab Initio Biotherapeutics, Inc.						Delaware
Allergan Ligand Retinoid Therapeutics, Inc.						Delaware
Cita NeuroPharmaceuticals Inc.						Canada
Crystal Bioscience, Inc.						California
CyDex Pharmaceuticals, Inc.						Delaware
Glycomed Incorporated						California
Icagen, LLC						Delaware
Ligand Biopharmaceuticals Incorporated						Delaware
Ligand Holdings UK Limited						England and Wales
Ligand JVR, Inc.						Delaware
Ligand Pharmaceuticals (Canada) Incorporated						Canada
Ligand Pharmaceuticals International, Inc.						Delaware
Ligand Pharmaceuticals UK Limited						United Kingdom
Ligand UK Development Limited						England and Wales
Ligand UK Group Limited						England and Wales
Ligand UK Limited						England and Wales
Ligand UK Research Limited						England and Wales
Metabasis Therapeutics, Inc.						Delaware
Neurogen Corporation						Delaware
OmniAb, Inc.						Delaware
OMT I, Inc.						Delaware
OMT II, Inc.						Delaware
Pfenex Inc.						Delaware
Pharmacopeia, LLC						Delaware
Seragen Incorporated						Delaware
Seragen Technology, Inc.						Delaware
Taurus Biosciences, LLC						Delaware
Vernalis Therapeutics Inc.						Delaware
xCella Biosciences, Inc.						Delaware