    <SEC-DOCUMENT>0000886163-22-000038-index.html : 20220422
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    <ACCEPTANCE-DATETIME>20220422161127
    ACCESSION NUMBER:		0000886163-22-000038
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		11
    CONFORMED PERIOD OF REPORT:	20220610
    FILED AS OF DATE:		20220422
    DATE AS OF CHANGE:		20220422

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			LIGAND PHARMACEUTICALS INC
    		CENTRAL INDEX KEY:			0000886163
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				770160744
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33093
    		FILM NUMBER:		22845613

    	BUSINESS ADDRESS:
    		STREET 1:		3911 SORRENTO VALLEY BLVD
    		STREET 2:		SUITE 110
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		858-550-7500

    	MAIL ADDRESS:
    		STREET 1:		3911 SORRENTO VALLEY BLVD
    		STREET 2:		SUITE 110
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>ligand-2022annualmeetingpr.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: ligand-2022annualmeetingpr.htm

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    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>a2021psuchart.jpg
    <TEXT>
    Document 2 - file: a2021psuchart.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>image.jpg
    <TEXT>
    Document 3 - file: image.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>image1.jpg
    <TEXT>
    Document 4 - file: image1.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>image2.jpg
    <TEXT>
    Document 5 - file: image2.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>image_0.jpg
    <TEXT>
    Document 6 - file: image_0.jpg

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    <SEQUENCE>7
    <FILENAME>image_2.jpg
    <TEXT>
    Document 7 - file: image_2.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>partneredpipeline_updated.jpg
    <TEXT>
    Document 8 - file: partneredpipeline_updated.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>picture1.jpg
    <TEXT>
    Document 9 - file: picture1.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>picture2.jpg
    <TEXT>
    Document 10 - file: picture2.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>stockgraph.jpg
    <TEXT>
    Document 11 - file: stockgraph.jpg

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