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Fair Value Measurement - Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) | Dec. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) | Jan. 31, 2010 USD ($) agreement
--- | --- | --- | ---
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Number of CVR agreements | agreement |  |  | 4
Transferred over Time | Phase 3 Clinical Trial |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Gross contract asset |  |  | $ 10,000,000
Maximum | Transferred over Time | Development, Regulatory, & Commercial Milestones and Tiered Royalties |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Investments |  |  | $ 375,000,000
Recurring |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | $ 166,864,000 | $ 321,586,000 |
Liabilities, fair value | 3,557,000 | 3,793,000 |
Recurring | Contingent liabilities - CyDex |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 84,000 | 349,000 |
Recurring | Contingent liabilities - Metabasis |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 3,429,000 | 3,358,000 |
Recurring | Liability for restricted investments owed to former licensees |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 44,000 | 86,000 |
Recurring | Short-term investments |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 103,742,000 | 290,697,000 |
Recurring | Investment in Viking common stock (2) |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 63,122,000 | 30,889,000 |
Recurring | Quoted Prices in Active Markets for Identical Assets (Level 1) |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 67,114,000 | 40,624,000 |
Liabilities, fair value | 44,000 | 86,000 |
Recurring | Quoted Prices in Active Markets for Identical Assets (Level 1) | Contingent liabilities - CyDex |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 0 | 0 |
Recurring | Quoted Prices in Active Markets for Identical Assets (Level 1) | Contingent liabilities - Metabasis |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 0 | 0 |
Recurring | Quoted Prices in Active Markets for Identical Assets (Level 1) | Liability for restricted investments owed to former licensees |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 44,000 | 86,000 |
Recurring | Quoted Prices in Active Markets for Identical Assets (Level 1) | Short-term investments |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 3,992,000 | 9,735,000 |
Recurring | Quoted Prices in Active Markets for Identical Assets (Level 1) | Investment in Viking common stock (2) |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 63,122,000 | 30,889,000 |
Recurring | Significant Other Observable Inputs (Level 2) |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 99,615,000 | 280,553,000 |
Liabilities, fair value | 3,429,000 | 3,358,000 |
Recurring | Significant Other Observable Inputs (Level 2) | Contingent liabilities - CyDex |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 0 | 0 |
Recurring | Significant Other Observable Inputs (Level 2) | Contingent liabilities - Metabasis |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 3,429,000 | 3,358,000 |
Recurring | Significant Other Observable Inputs (Level 2) | Liability for restricted investments owed to former licensees |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 0 | 0 |
Recurring | Significant Other Observable Inputs (Level 2) | Short-term investments |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 99,615,000 | 280,553,000 |
Recurring | Significant Other Observable Inputs (Level 2) | Investment in Viking common stock (2) |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 0 | 0 |
Recurring | Significant Unobservable Inputs (Level 3) |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 135,000 | 409,000 |
Liabilities, fair value | 84,000 |  |
Recurring | Significant Unobservable Inputs (Level 3) | Contingent liabilities - CyDex |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 84,000 | 349,000 |
Recurring | Significant Unobservable Inputs (Level 3) | Contingent liabilities - Metabasis |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 0 | 0 |
Recurring | Significant Unobservable Inputs (Level 3) | Liability for restricted investments owed to former licensees |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Liabilities, fair value | 0 | 0 |
Recurring | Significant Unobservable Inputs (Level 3) | Short-term investments |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | 135,000 | 409,000 |
Recurring | Significant Unobservable Inputs (Level 3) | Investment in Viking common stock (2) |  |  |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |  |  |
Assets, fair value | $ 0 | $ 0 |

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