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Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details)
12 Months Ended
Dec. 31, 2023
USD ($)
segment
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2007
$ / shares
Jan. 31, 2010
right
Basis of Presentation          
Number of reportable segment | segment 1        
Increase (decrease) of allowance for credit loss $ 200,000 $ (300,000) $ 10,000.00    
Write-downs related to obsolete inventory 200,000 1,100,000 $ 0    
Inventory 23,969,000 13,294,000      
Revenue recognized $ 100,000 400,000      
Dividend declared (in USD per share) | $ / shares       $ 2.50  
Dividend yield          
Basis of Presentation          
Measurement input (as a percent) 0        
PSUs          
Basis of Presentation          
Award vesting period (in years) 3 years        
Employee Stock Option | 2002 Stock Incentive Plan          
Basis of Presentation          
Award expiration period (in years) 10 years        
Employee Stock Option | 2002 Stock Incentive Plan | Vest 1/8 on the six month anniversary of the date of grant          
Basis of Presentation          
Award vesting period (in years) 6 months        
Award vesting right (as a percent) 12.50%        
Employee Stock Option | 2002 Stock Incentive Plan | Vest 1/48 each month for forty-two months          
Basis of Presentation          
Award vesting period (in years) 42 months        
Award vesting right (as a percent) 2.08%        
RSUs and PSUs          
Basis of Presentation          
Award vesting period (in years) 3 years        
Metabasis Therapeutics          
Basis of Presentation          
Number of contingent value rights | right         4
Minimum          
Basis of Presentation          
Property and equipment, useful life (in years) 1 year        
Minimum | PSUs          
Basis of Presentation          
Award vesting right (as a percent) 0.00%        
Maximum          
Basis of Presentation          
Property and equipment, useful life (in years) 9 years        
Maximum | PSUs          
Basis of Presentation          
Award vesting right (as a percent) 200.00%        
Captisol          
Basis of Presentation          
Inventory $ 4,600,000 $ 5,900,000