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Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details)
shares in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
USD ($)
position
shares
Jun. 30, 2023
USD ($)
shares
Jun. 30, 2024
USD ($)
segment
position
shares
Jun. 30, 2023
USD ($)
shares
Jul. 08, 2024
USD ($)
May 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Sep. 18, 2023
contract
Property, Plant and Equipment                
Number of reportable segments | segment     1          
Revenue recognized that was previously deferred $ 450,000 $ 20,000.00 $ 1,000,000 $ 120,000        
Sale of Viking common stock (in shares) | shares 0   700          
Gain on sale of Viking common stock     $ 60,000,000          
Number of positions in an unrealized loss position | position 78   78          
Unrealized losses $ 100,000   $ 100,000          
Amortized cost 50,000.00   50,000.00          
Credit losses related to available-for-sale debt securities 0 0 0 0        
(Decrease) increase in allowance for credit losses 180,000 (90,000.00) (120,000) 50,000.00        
Inventory write-down 200,000 $ 0 200,000 0        
Inventory $ 18,672,000   $ 18,672,000       $ 23,969,000  
Gain (loss) on derivative       $ 0        
Derivative, Gain (Loss), Statement of Income or Comprehensive Income [Extensible Enumeration] Gain (Loss) on Investments   Gain (Loss) on Investments          
Employee retention credit $ 2,300,000   $ 2,300,000          
Financial royalty liability current $ 1,200,000   $ 1,200,000          
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares 2,347 4,862 2,177 4,612        
Share-based Compensation                
Property, Plant and Equipment                
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares 400              
Performance Shares                
Property, Plant and Equipment                
Performance period for awards (in years)     3 years          
APEIRON | Subsequent Event                
Property, Plant and Equipment                
Deferred transaction costs         $ 3,500,000      
Minimum | Performance Shares                
Property, Plant and Equipment                
Payout range (as a percent)     0.00%          
Maximum | Performance Shares                
Property, Plant and Equipment                
Payout range (as a percent)     200.00%          
Other Derivatives                
Property, Plant and Equipment                
Gain (loss) on derivative $ 1,500,000   $ 1,700,000          
Agenus Partnered Program                
Property, Plant and Equipment                
Additional maximum investment           $ 25,000,000    
Percentage of milestones (as a percent)               50.00%
Agenus Partnered Program | Primordial Genetics                
Property, Plant and Equipment                
Number of contracts | contract               2
Viking | Collars                
Property, Plant and Equipment                
Gain (loss) on derivative 15,200,000   15,200,000          
Palvella                
Property, Plant and Equipment                
Convertible note $ 2,500,000   $ 2,500,000          
Convertible note maturity period 3 years   3 years          
Palvella | Minimum                
Property, Plant and Equipment                
Interest in sales revenue (as a percent) 8.00%   8.00%          
Palvella | Maximum                
Property, Plant and Equipment                
Interest in sales revenue (as a percent) 9.80%   9.80%          
Palvella | Royalty Agreements                
Property, Plant and Equipment                
Additional royalties receivable under sales-based milestones $ 5,000,000   $ 5,000,000          
Captisol                
Property, Plant and Equipment                
Inventory $ 4,200,000   $ 4,200,000       $ 4,600,000