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Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details)
shares in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended
Jan. 31, 2010
cvr
Sep. 30, 2024
USD ($)
position
shares
Sep. 30, 2023
USD ($)
shares
Sep. 30, 2024
USD ($)
position
segment
shares
Sep. 30, 2023
USD ($)
shares
Jun. 30, 2024
USD ($)
May 29, 2024
USD ($)
Dec. 31, 2023
USD ($)
Sep. 18, 2023
contract
Property, Plant and Equipment                  
Number of reportable segments | segment       1          
Revenue recognized that was previously deferred   $ 200,000 $ 0 $ 1,200,000 $ 0        
Sale of Viking common stock (in shares) | shares   0 0 700 4,500        
Gain on sale of Viking common stock       $ 60,000,000 $ 37,200,000        
Number of positions in an unrealized loss position | position   32   32          
Unrealized losses   $ (10,000.00)   $ (10,000.00)          
Amortized cost       50,000.00          
Credit losses related to available-for-sale debt securities   0 $ 0   0        
(Decrease) increase in allowance for credit losses   (10,000.00) 100,000 (130,000) 140,000        
Inventory write-down   100,000 0 200,000 0        
Inventory   16,740,000   16,740,000       $ 23,969,000  
Fair value adjustments to partner program derivatives   $ (7,812,000) 0 $ (7,812,000) 0        
Derivative, Gain (Loss), Statement of Income or Comprehensive Income [Extensible Enumeration]   Gain (Loss) on Investments   Gain (Loss) on Investments          
Received amount expended   $ 5,675,000 $ 5,532,000 $ 17,000,000 $ 19,049,000        
Employee retention credit   2,300,000   2,300,000          
Financial royalty liability current   6,600,000   6,600,000          
Prepaid expense   $ 2,200,000   $ 2,200,000          
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares   1,099 4,762 1,815 4,663        
Metabasis                  
Property, Plant and Equipment                  
Number of CVRs issued per acquiree share | cvr 4                
Share-based Compensation                  
Property, Plant and Equipment                  
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares   700 300            
Performance Shares                  
Property, Plant and Equipment                  
Performance period for awards (in years)       3 years          
Minimum | Performance Shares                  
Property, Plant and Equipment                  
Payout range (as a percent)       0.00%          
Maximum | Performance Shares                  
Property, Plant and Equipment                  
Payout range (as a percent)       200.00%          
Other Derivatives                  
Property, Plant and Equipment                  
Fair value adjustments to partner program derivatives   $ (8,000,000)   $ (6,800,000)          
Agenus Partnered Program                  
Property, Plant and Equipment                  
Additional maximum investment             $ 25,000,000    
Percentage of milestones (as a percent)                 50.00%
Agenus Partnered Program | Primordial Genetics                  
Property, Plant and Equipment                  
Number of contracts | contract                 2
Viking | Collars                  
Property, Plant and Equipment                  
Fair value adjustments to partner program derivatives   (7,900,000)   7,300,000          
Agenus, Inc. | Partner Programs                  
Property, Plant and Equipment                  
Fair value adjustments to partner program derivatives   (7,200,000)   (7,200,000)          
Primrose Bio                  
Property, Plant and Equipment                  
Fair value adjustments to partner program derivatives   $ (600,000) $ 0 $ (600,000) $ 0        
Palvella                  
Property, Plant and Equipment                  
Convertible note           $ 2,500,000      
Convertible note maturity period (in years)           3 years      
Palvella | Minimum                  
Property, Plant and Equipment                  
Interest in sales revenue (as a percent)   8.00%   8.00%          
Palvella | Maximum                  
Property, Plant and Equipment                  
Interest in sales revenue (as a percent)   9.80%   9.80%          
Palvella | Royalty Agreements                  
Property, Plant and Equipment                  
Additional royalties receivable under sales-based milestones   $ 5,000,000   $ 5,000,000          
Received amount expended       700,000          
Captisol                  
Property, Plant and Equipment                  
Inventory   $ 3,300,000   $ 3,300,000       $ 4,600,000