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Pay vs Performance Disclosure - USD ($) | 12 Months Ended
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Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Pay vs Performance Disclosure |  |  |  |
Pay vs Performance Disclosure, Table |
|  |  |  |  |  |  | Value of Initial Fixed $100 Investment Based on: |  |
Year | Summary Compensation Table Total for PEO Todd C. Davis ($) | Summary Compensation Table Total for PEO John L. Higgins ($) | Compensation Actually Paid to PEO Todd C. Davis ($)(1) | Compensation Actually Paid for PEO John L. Higgins ($) | Average Summary Compensation Table Total for Non-PEO NEOs ($) | Average Compensation Actually Paid to Non-PEO NEOs ($)(2)(3) | Total Shareholder Return ($) | Peer Group Total Shareholder Return ($)(4) | Net Income (Loss) ($ thousands) | Revenue ($ thousands)
2023 | 6,216,518 |  | — |  | 5,060,695 |  | — |  | 2,788,000 |  | 2,366,969 |  | 98.71 |  | 118.87 |  | 52,154 |  | 131,314 |
2022 | 5,195,169 |  | 16,764,990 |  | 4,977,510 |  | 12,243,958 |  | 3,852,731 |  | 2,922,612 |  | 92.32 |  | 113.65 |  | (33,361) |  | 196,245 |
2021 | — |  | 9,587,211 |  | — |  | 15,958,534 |  | 4,996,210 |  | 7,722,154 |  | 148.11 |  | 126.45 |  | 57,138 |  | 241,544 |
2020 | — |  | 5,842,767 |  | — |  | 6,788,815 |  | 2,846,812 |  | 3,246,826 |  | 95.36 |  | 126.42 |  | (2,985) |  | 163,562 |
Company Selected Measure Name | Revenue |  |  |
Named Executive Officers, Footnote | Amounts represent compensation actually paid to our PEO and the average compensation actually paid to our remaining NEOs for the relevant fiscal year, as determined under SEC rules (and described below), which includes the individuals indicated in the table below for each fiscal year:
Year | PEO | Non-PEO NEOs
2023 | Todd C. Davis | Matthew Korenberg, Tavo Espinoza, and Andrew Reardon
2022 | Todd C. Davis, John L. Higgins | Matthew Korenberg, Tavo Espinoza, Andrew Reardon, Matthew W. Foehr, and Charles S. Berkman
2021 | John L. Higgins | Matthew Korenberg, Matthew W. Foehr, and Charles S. Berkman
2020 | John L. Higgins | Matthew Korenberg, Matthew W. Foehr, and Charles S. Berkman
Peer Group Issuers, Footnote | (4) For the relevant fiscal year, the Peer Group TSR is from the NASDAQ Biotechnology Index, which we also utilize in the stock performance graph required by Item 201(e) of Regulation S-K included in our Annual Report for the year ended December 31, 2023. The calculation of the TSR assumes an initial investment of $100 on January 1, 2019 through December 31 of the applicable year in the table above, assuming all dividends are reinvested. |  |  |
Adjustment To PEO Compensation, Footnote | Compensation actually paid to our current PEO, Todd C. Davis for the current fiscal year is presented in the following table:
Year | Summary Compensation Table Total for Todd C. Davis ($) | Exclusion of Stock Awards and Option Awards for Todd C. Davis ($) | Inclusion of Equity Values for Todd C. Davis ($) | Compensation Actually Paid to Todd C. Davis ($)
2023 | 6,216,518 |  | (5,166,551) |  | 4,010,728 |  | 5,060,695 |
ompensation actually paid to our NEOs represents the “Total” compensation reported in the Summary Compensation Table, as adjusted as follows:
|  | Adjustments(1)
| Year | Year-End ASC 718 Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year for ($) | Change in ASC 718 Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards ($) | Vesting-Date ASC 718 Fair Value of Equity Awards Granted During Year that Vested During Year ($) | Change in ASC 718 Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year ($) | ASC 718 Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year ($) | Total - Inclusion of Equity Value ($)
Todd C. Davis | 2023 | 4,302,070 |  | (354,271) |  | 246,646 |  | (183,717) |  | — |  | 4,010,728 |
Non-PEO NEOs | 2023 | 1,751,529 |  | (69,868) |  | 100,496 |  | (98,262) |  | — |  | 1,683,895 |
(1) Fair value or change in fair value, as applicable, of equity awards in the “Compensation Actually Paid” columns was determined by reference to (i) for solely service-vesting RSU awards, the closing price per share on the applicable year-end dates or, in the case of vesting dates, the closing price per share on the applicable vesting dates; (ii) for stock options, a Black-Scholes value as of the applicable year-end or vesting dates, determined based on the same methodology as used to determine grant date fair value but using the closing stock price on the applicable revaluation date as the current market price and with an expected life set equal to the remaining life of the award in the case of underwater stock options and, in the case of in the money options, an expected life equal to the original ratio of expected life relative to the ten year contractual life times the remaining life as of the applicable revaluation date, and in all cases based on volatility and risk free rates determined as of the revaluation date based on the expected life period and based on an expected dividend yield based on our dividend yield methodology used for valuing stock options generally; and (iii) for PSUs, calculated by a Monte Carlo simulation model as of the applicable revaluation dates, which utilizes multiple input variables, including expected volatility of our stock price and other assumptions appropriate for determining fair value, to estimate the probability of satisfying the performance objective established for the award, including the expected volatility of our stock price relative to the applicable comparative index and a risk-free interest rate. For additional information about the assumptions used to value our stock and option awards, please see Note 10 of the Notes to Consolidated Financial Statements included in our Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on February 29, 2024, and our Annual Report on Form 10-K for prior years. |  |  |
Non-PEO NEO Average Total Compensation Amount | $ 2,788,000 | $ 3,852,731 | $ 4,996,210 | $ 2,846,812
Non-PEO NEO Average Compensation Actually Paid Amount | $ 2,366,969 | 2,922,612 | 7,722,154 | 3,246,826
Adjustment to Non-PEO NEO Compensation Footnote | Average compensation actually paid to our non-PEO NEOs for the current fiscal year is presented in the following table:
Year | Average Summary Compensation Table Total for Non-PEO NEOs | Average Exclusion of Stock Awards and Option Awards for Non-PEO NEOs | Average Inclusion of Equity Values for Non-PEO NEOs | Average Compensation Actually Paid to Non-PEO NEOs
2023 | 2,788,000 |  | (2,104,926) |  | 1,683,895 |  | 2,366,969 |
ompensation actually paid to our NEOs represents the “Total” compensation reported in the Summary Compensation Table, as adjusted as follows:
|  | Adjustments(1)
| Year | Year-End ASC 718 Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year for ($) | Change in ASC 718 Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards ($) | Vesting-Date ASC 718 Fair Value of Equity Awards Granted During Year that Vested During Year ($) | Change in ASC 718 Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year ($) | ASC 718 Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year ($) | Total - Inclusion of Equity Value ($)
Todd C. Davis | 2023 | 4,302,070 |  | (354,271) |  | 246,646 |  | (183,717) |  | — |  | 4,010,728 |
Non-PEO NEOs | 2023 | 1,751,529 |  | (69,868) |  | 100,496 |  | (98,262) |  | — |  | 1,683,895 |
(1) Fair value or change in fair value, as applicable, of equity awards in the “Compensation Actually Paid” columns was determined by reference to (i) for solely service-vesting RSU awards, the closing price per share on the applicable year-end dates or, in the case of vesting dates, the closing price per share on the applicable vesting dates; (ii) for stock options, a Black-Scholes value as of the applicable year-end or vesting dates, determined based on the same methodology as used to determine grant date fair value but using the closing stock price on the applicable revaluation date as the current market price and with an expected life set equal to the remaining life of the award in the case of underwater stock options and, in the case of in the money options, an expected life equal to the original ratio of expected life relative to the ten year contractual life times the remaining life as of the applicable revaluation date, and in all cases based on volatility and risk free rates determined as of the revaluation date based on the expected life period and based on an expected dividend yield based on our dividend yield methodology used for valuing stock options generally; and (iii) for PSUs, calculated by a Monte Carlo simulation model as of the applicable revaluation dates, which utilizes multiple input variables, including expected volatility of our stock price and other assumptions appropriate for determining fair value, to estimate the probability of satisfying the performance objective established for the award, including the expected volatility of our stock price relative to the applicable comparative index and a risk-free interest rate. For additional information about the assumptions used to value our stock and option awards, please see Note 10 of the Notes to Consolidated Financial Statements included in our Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on February 29, 2024, and our Annual Report on Form 10-K for prior years. |  |  |
Compensation Actually Paid vs. Total Shareholder Return |  |  |  |
Compensation Actually Paid vs. Net Income |  |  |  |
Compensation Actually Paid vs. Company Selected Measure |  |  |  |
Total Shareholder Return Vs Peer Group |  |  |  |
Tabular List, Table | Revenue •Adjusted EBITDA •Total Shareholder Return |  |  |
Total Shareholder Return Amount | $ 98.71 | 92.32 | 148.11 | 95.36
Peer Group Total Shareholder Return Amount | 118.87 | 113.65 | 126.45 | 126.42
Net Income (Loss) | $ 52,154,000 | $ (33,361,000) | $ 57,138,000 | $ (2,985,000)
Company Selected Measure Amount | 131,314,000 | 196,245,000 | 241,544,000 | 163,562,000
PEO Name | Todd C. Davis |  | John L. Higgins | John L. Higgins
Measure:: 1 |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Name | Revenue |  |  |
Measure:: 2 |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Name | Adjusted EBITDA |  |  |
Measure:: 3 |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Name | Total Shareholder Return |  |  |
Todd C. Davis [Member] |  |  |  |
Pay vs Performance Disclosure |  |  |  |
PEO Total Compensation Amount | $ 6,216,518 | $ 5,195,169 | $ 0 | $ 0
PEO Actually Paid Compensation Amount | 5,060,695 | $ 4,977,510 | 0 | 0
PEO Name |  | Todd C. Davis |  |
John L. Higgins [Member] |  |  |  |
Pay vs Performance Disclosure |  |  |  |
PEO Total Compensation Amount | 0 | $ 16,764,990 | 9,587,211 | 5,842,767
PEO Actually Paid Compensation Amount | 0 | $ 12,243,958 | $ 15,958,534 | $ 6,788,815
PEO Name |  | John L. Higgins |  |
PEO | Todd C. Davis [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | (5,166,551) |  |  |
PEO | Todd C. Davis [Member] | Equity Awards Adjustments, Excluding Value Reported in Compensation Table |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | 4,010,728 |  |  |
PEO | Todd C. Davis [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | 4,302,070 |  |  |
PEO | Todd C. Davis [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | (354,271) |  |  |
PEO | Todd C. Davis [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | 246,646 |  |  |
PEO | Todd C. Davis [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | (183,717) |  |  |
PEO | Todd C. Davis [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | 0 |  |  |
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | (2,104,926) |  |  |
Non-PEO NEO | Equity Awards Adjustments, Excluding Value Reported in Compensation Table |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | 1,683,895 |  |  |
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | 1,751,529 |  |  |
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | (69,868) |  |  |
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | 100,496 |  |  |
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | (98,262) |  |  |
Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year |  |  |  |
Pay vs Performance Disclosure |  |  |  |
Adjustment to Compensation, Amount | $ 0 |  |  |

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