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Balance Sheet Account Details - Narrative (Details) | 3 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Jun. 30, 2024 USD ($) | Dec. 31, 2024 USD ($) position $ / shares shares | Dec. 31, 2023 USD ($) shares | Dec. 31, 2022 USD ($) shares | Dec. 16, 2024 shares
Schedule of Investments |  |  |  |  |
Number of positions in an unrealized loss position | position |  | 45 |  |  |
Unrealized losses |  | $ 31,000 | $ 14,000 |  |
Amortized cost | $ 50,000.00 |  |  |  |
Credit losses related to available-for-sale debt securities |  | 0 | 0 |  |
Investment in Viking common stock |  | 40,200,000 | 32,200,000 |  |
Gain from short-term investments |  | 75,024,000 | 46,365,000 | $ 28,540,000 |
Depreciation expense |  | 2,300,000 | 2,900,000 | 3,800,000 |
Amortization of intangibles |  | 32,959,000 | 33,654,000 | 34,237,000 |
Estimated amortization expense for 2025 |  | 32,700,000 |  |  |
Estimated amortization expense for 2026 |  | 32,700,000 |  |  |
Estimated amortization expense for 2027 |  | 32,700,000 |  |  |
Estimated amortization expense for 2028 |  | 32,700,000 |  |  |
Estimated amortization expense for 2029 |  | 32,700,000 |  |  |
Impairment loss of financial royalty assets |  | 0 | 0 | 0 |
Fair value adjustments to partner program derivatives |  | $ (15,055,000) | $ 0 | 0 |
Preferred stock outstanding (in shares) | shares |  | 0 | 0 |  |
Received amount expended |  | $ 21,425,000 | $ 24,537,000 | $ 36,082,000 |
Financial royalty liability current |  | 10,000,000.0 |  |  |
Vikings |  |  |  |  |
Schedule of Investments |  |  |  |  |
Vikings common stock outstanding |  | 1,000,000.0 |  |  |
Series C Preferred Stock |  |  |  |  |
Schedule of Investments |  |  |  |  |
Exchange ratio |  |  |  |  | 0.3095
Preferred stock outstanding (in shares) | shares |  |  |  |  | 189,112
Common Stock |  |  |  |  |
Schedule of Investments |  |  |  |  |
Convertible preferred stock (in shares) | shares |  |  |  |  | 58,524
Other Derivatives |  |  |  |  |
Schedule of Investments |  |  |  |  |
Fair value adjustments to partner program derivatives |  | (12,100,000) |  |  |
Collars | Vikings |  |  |  |  |
Schedule of Investments |  |  |  |  |
Fair value adjustments to partner program derivatives |  | 7,100,000 |  |  |
Primrose Bio |  |  |  |  |
Schedule of Investments |  |  |  |  |
Fair value adjustments to partner program derivatives |  | (100,000) | $ 300,000 |  |
Palvella |  |  |  |  |
Schedule of Investments |  |  |  |  |
Convertible note | $ 2,500,000 |  |  |  |
Convertible note maturity period (in years) | 3 years |  |  |  |
Preferred stock shares, amount |  | $ 2,600,000 |  |  |
Shares issued upon conversion of preferred stock (in shares) | shares |  | 184,595 |  |  |
Debt conversion price per share (in USD per share) | $ / shares |  | $ 13.9965 |  |  |
Palvella | Royalty Agreements |  |  |  |  |
Schedule of Investments |  |  |  |  |
Additional royalties receivable under sales-based milestones |  | $ 5,000,000 |  |  |
Received amount expended |  | 1,200,000 |  |  |
Agenus, Inc. | Partner Programs |  |  |  |  |
Schedule of Investments |  |  |  |  |
Fair value adjustments to partner program derivatives |  | $ (15,000,000.0) |  |  |
Viking Therapeutics, Inc. |  |  |  |  |
Schedule of Investments |  |  |  |  |
Stock sold of equity method investee (in shares) | shares |  | 700,000 | 5,000,000.0 | 0 |
Gain from short-term investments |  | $ 60,000,000.0 | $ 44,400,000 |  |
Minimum |  |  |  |  |
Schedule of Investments |  |  |  |  |
Property and equipment, useful life (in years) |  | 1 year |  |  |
Minimum | Palvella |  |  |  |  |
Schedule of Investments |  |  |  |  |
Interest in sales revenue (as a percent) |  | 8.00% |  |  |
Maximum |  |  |  |  |
Schedule of Investments |  |  |  |  |
Property and equipment, useful life (in years) |  | 9 years |  |  |
Finite-lived intangible asset, useful life (in years) |  | 20 years |  |  |
Maximum | Palvella |  |  |  |  |
Schedule of Investments |  |  |  |  |
Interest in sales revenue (as a percent) |  | 9.80% |  |  |

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