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Basis of Presentation and Summary of Significant Accounting Policies - Narrative (Details) shares in Thousands | 3 Months Ended |  |  |
--- | --- | --- | --- | ---
Mar. 31, 2025 USD ($) position segment shares | Mar. 31, 2024 USD ($) shares | Dec. 31, 2024 USD ($) | Sep. 18, 2023 contract | Jan. 31, 2010 cvr
Property, Plant and Equipment |  |  |  |  |
Number of operating segments | segment | 1 |  |  |  |
Number of reportable segments | segment | 1 |  |  |  |
Revenue recognized that was previously deferred | $ 300,000 | $ 500,000 |  |  |
Sale of Viking common stock (in shares) | shares | 0 | 700 |  |  |
Gain on sale of Viking common stock |  | $ 60,000,000 |  |  |
Number of positions in an unrealized loss position | position | 33 |  |  |  |
Unrealized losses | $ (20,000.00) |  |  |  |
Credit losses related to available-for-sale debt securities | 0 |  |  |  |
Increase (decrease) in allowance for credit losses | 300,000 | (300,000) |  |  |
Inventory | 14,614,000 |  | $ 14,114,000 |  |
Fair value adjustments to partner program derivatives | 443,000 | 0 |  |  |
Loss from derivative instrument | $ (600,000) |  |  |  |
Derivative, Loss, Statement of Income or Comprehensive Income [Extensible Enumeration] | Other Nonoperating Income (Expense) |  |  |  |
Losses from equity method investment in Primrose Bio | $ 0 | (2,352,000) |  |  |
Observable price changes | 0 | 0 |  |  |
Received amount expended | 50,085,000 | $ 5,971,000 |  |  |
Financial royalty liability current | $ 10,100,000 |  | $ 10,000,000 |  |
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares | 761 | 2,007 |  |  |
Primrose Bio |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Investment owned, net assets, percentage | 31.40% |  | 31.40% |  |
Losses from equity method investment in Primrose Bio |  | $ (2,400,000) |  |  |
Equity method investment in Primrose Bio |  |  | $ 0 |  |
Impairment of equity method investment | $ 0 | 0 |  |  |
Share-based Compensation |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Potentially dilutive shares excluded from calculation due to anti-dilutive effect (in shares) | shares | 800 |  |  |  |
Performance Shares |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Performance period for awards (in years) | 3 years |  |  |  |
Metabasis Therapeutics |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Number of contingent value rights issued | cvr |  |  |  |  | 4
Minimum | Performance Shares |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Payout range (as a percent) | 0.00% |  |  |  |
Maximum | Performance Shares |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Payout range (as a percent) | 200.00% |  |  |  |
Agenus Partnered Program |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Percentage of milestones (as a percent) |  |  |  | 50.00% |
Agenus Partnered Program | Primordial Genetics |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Number of contracts | contract |  |  |  | 2 |
Agenus, Inc. | Partner Programs |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Fair value adjustments to partner program derivatives | $ 300,000 |  |  |  |
Primrose Bio |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Fair value adjustments to partner program derivatives | $ 100,000 | 0 |  |  |
Gain on derivative instrument |  | $ 200,000 |  |  |
Derivative, Gain, Statement of Income or Comprehensive Income [Extensible Enumeration] |  | Other Nonoperating Income (Expense) |  |  |
Palvella | Minimum |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Interest in sales revenue (as a percent) | 8.00% |  |  |  |
Palvella | Maximum |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Interest in sales revenue (as a percent) | 9.80% |  |  |  |
Palvella | Royalty Agreements |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Additional royalties receivable under sales-based milestones | $ 5,000,000 |  |  |  |
Received amount expended | 2,000,000 |  |  |  |
Captisol |  |  |  |  |
Property, Plant and Equipment |  |  |  |  |
Inventory | $ 2,800,000 |  | $ 3,100,000 |  |

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