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Castle Creek and Agenus Transactions (Details)
$ / shares in Units, $ in Thousands
 6 Months Ended
Feb. 24, 2025
USD ($)
May 29, 2024
USD ($)
$ / shares
shares
Jun. 30, 2025
USD ($)
Jun. 30, 2024
USD ($)
Dec. 31, 2024
USD ($)
Asset Acquisition          
Cash paid for Palvella notes receivable     $ 0 $ 2,500  
Net carrying value     203,832   $ 195,049
Agenus, Inc.          
Asset Acquisition          
Net carrying value   $ 75,000 40,407   $ 40,407
Royalties right to receive (as a percent)   18.75%      
Maximum capital sourcing   $ 100,000      
Maximum financing royalty asset   $ 200,000      
Warrants term (in years)   5 years      
Securities called by warrants (in shares) | shares   867,052      
Exercise price (in USD per share) | $ / shares   $ 17.3      
Agenus, Inc. | BMS-986442          
Asset Acquisition          
Future milestones right to receive (as a percent)   31.875%      
Agenus, Inc. | AGEN2373          
Asset Acquisition          
Future milestones right to receive (as a percent)   31.875%      
Agenus, Inc. | INCAGN2385          
Asset Acquisition          
Future milestones right to receive (as a percent)   31.875%      
Agenus, Inc. | INCAGN2390          
Asset Acquisition          
Future milestones right to receive (as a percent)   31.875%      
Agenus, Inc. | MK-4830          
Asset Acquisition          
Future milestones right to receive (as a percent)   31.875%      
Agenus, Inc. | UGN-301          
Asset Acquisition          
Future milestones right to receive (as a percent)   31.875%      
Agenus, Inc. | BOT/BAL          
Asset Acquisition          
Future royalties (as a percent)   2.625%      
Agenus Partnered Program          
Asset Acquisition          
Additional maximum investment   $ 25,000      
Castle Creek Investment          
Asset Acquisition          
Payments to acquire productive assets $ 50,000   50,100    
Receivable with imputed interest, face amount 8,300        
Cash paid for Palvella notes receivable $ 1,800        
Payments for repurchase of warrants     5,800    
Recognized research and development expense     $ 44,300    
Castle Creek Investment | Option Volatility          
Asset Acquisition          
Derivative liability, measurement input 1.10        
Castle Creek Investment | Risk Free Interest Rate          
Asset Acquisition          
Derivative liability, measurement input 0.042        
Purchasers | Castle Creek Investment          
Asset Acquisition          
Payments to acquire productive assets $ 75,000        
Other Purchasers | Castle Creek Investment          
Asset Acquisition          
Payments to acquire productive assets $ 25,000