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Basis of Presentation and Summary of Significant Accounting Policies - Segment Profit or Loss (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Revenue, Major Customer        
Total revenues and other income $ 115,461 $ 51,812 $ 208,421 $ 124,321
Share-based compensation     (32,579) (33,565)
Other segment items:        
Amortization of intangibles (8,097) (8,258) (24,612) (24,701)
Interest expense (910) (741) (2,930) (2,154)
Net income (loss) 54,931 3,143 27,159 (12,969)
Other expense items, net 34,500 14,200 111,600 34,600
Castle Creek Investment        
Other segment items:        
Recognized research and development expense     44,300  
Orchestra Warrant        
Other segment items:        
Recognized research and development expense     17,800  
Income from financial royalty assets        
Revenue, Major Customer        
Total revenues and other income 6,425 5,157 18,640 6,454
Other segment items:        
Financial royalty assets impairment       26,500
Development and Licensing of Biopharmaceutical Assets        
Revenue, Major Customer        
Total revenues and other income 115,461 51,812 208,421 124,321
Share-based compensation (14,746) (15,171) (32,579) (33,565)
Other segment items:        
Amortization of intangibles (8,097) (8,258) (24,612) (24,701)
Depreciation of property and equipment (172) (736) (949) (1,911)
Interest income 3,874 1,347 7,266 6,124
Interest expense (910) (741) (2,930) (2,154)
Other 21,863 (35,425) (74,948) (41,058)
Net income (loss) $ 117,273 $ (7,172) $ 79,669 $ 27,056