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Amount of consideration transferred in asset acquisition. Includes, but is not limited to, cash, liability incurred by acquirer, and equity interest issued by acquirer.

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Exercise price per share or per unit of warrants or rights outstanding.

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Amount of cash outflow, made soon after acquisition date of business combination, to settle contingent consideration liability.

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The cash outflow for purchases of and capital improvements on property, plant and equipment (capital expenditures), software, and other intangible assets.

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Investment Transactions (Details) $ / shares in Units, $ in Thousands					9 Months Ended
	Sep. 24, 2025 USD ($) installment shares	Aug. 04, 2025 USD ($) $ / shares	Feb. 24, 2025 USD ($)	May 29, 2024 USD ($) $ / shares shares	Sep. 30, 2025 USD ($)	Sep. 30, 2024 USD ($)	Dec. 31, 2024 USD ($)	May 24, 2024
Asset Acquisition
Cash paid for InvIOs investment					$ 0	$ 4,196
Cash paid for Palvella notes receivable					0	$ 2,500
Net carrying value					218,748		$ 195,049
Agenus Bot/Bal
Asset Acquisition
Securities called by warrants (in shares) \| shares				867,052
Warrants term (in years)				5 years
Net carrying value				$ 75,000
Royalties right to receive (as a percent)				18.75%
Maximum capital sourcing				$ 100,000
Maximum financing royalty asset				$ 200,000
Exercise price (in USD per share) \| $ / shares				$ 17.3
Agenus Bot/Bal \| BMS-986442
Asset Acquisition
Future milestones right to receive (as a percent)				31.875%
Agenus Bot/Bal \| AGEN2373
Asset Acquisition
Future milestones right to receive (as a percent)				31.875%
Agenus Bot/Bal \| INCAGN2385
Asset Acquisition
Future milestones right to receive (as a percent)				31.875%
Agenus Bot/Bal \| INCAGN2390
Asset Acquisition
Future milestones right to receive (as a percent)				31.875%
Agenus Bot/Bal \| MK-4830
Asset Acquisition
Future milestones right to receive (as a percent)				31.875%
Agenus Bot/Bal \| UGN-301
Asset Acquisition
Future milestones right to receive (as a percent)				31.875%
Agenus Bot/Bal \| BOT/BAL
Asset Acquisition
Future royalties (as a percent)				2.625%
Agenus Partnered Program
Asset Acquisition
Additional maximum investment				$ 25,000
Castle Creek Investment
Asset Acquisition
Payments for repurchase of warrants					5,800
Recognized research and development expense					44,300
Payments to acquire productive assets			$ 50,000		50,100
Receivable with imputed interest, face amount			8,300
Cash paid for Palvella notes receivable			1,800
Castle Creek Investment \| Purchasers
Asset Acquisition
Payments to acquire productive assets			75,000
Castle Creek Investment \| Other Purchasers
Asset Acquisition
Payments to acquire productive assets			$ 25,000
Orchestra BioMed
Asset Acquisition
Cash paid for InvIOs investment		$ 5,000
Price per share \| $ / shares		$ 2.75
Orchestra Warrant
Asset Acquisition
Payments for repurchase of warrants		$ 2,300
Recognized research and development expense					$ 17,800
Orchestra BioMed
Asset Acquisition
Committed capital		25,000
Investment amount, at closing		20,000
Investment amount, to be funded		15,000
Contracted royalty revenue		$ 100,000
Option Volatility \| Agenus Warrant
Asset Acquisition
Warrant measurement input (as a percent)					1.14			0.84
Option Volatility \| Minimum
Asset Acquisition
Warrant measurement input (as a percent)	0.32
Option Volatility \| Maximum
Asset Acquisition
Warrant measurement input (as a percent)	0.33
Risk Free Interest Rate \| Agenus Warrant
Asset Acquisition
Warrant measurement input (as a percent)					0.036			0.047
Risk Free Interest Rate \| Minimum
Asset Acquisition
Warrant measurement input (as a percent)					0.047
Risk Free Interest Rate \| Maximum
Asset Acquisition
Warrant measurement input (as a percent)	0.048
Acecor Warrants
Asset Acquisition
Securities called by warrants (in shares) \| shares	1,002,739
Warrants term (in years)	10 years
Payments for repurchase of warrants	$ 500
Orchestra Warrants \| Option Volatility \| Minimum
Asset Acquisition
Warrant measurement input (as a percent)	0.73
Orchestra Warrants \| Option Volatility \| Maximum
Asset Acquisition
Warrant measurement input (as a percent)	0.72
Orchestra Warrants \| Risk Free Interest Rate \| Minimum
Asset Acquisition
Warrant measurement input (as a percent)					0.044
Orchestra Warrants \| Risk Free Interest Rate \| Maximum
Asset Acquisition
Warrant measurement input (as a percent)					0.042
Castle Creek Warrant \| Option Volatility \| Minimum
Asset Acquisition
Warrant measurement input (as a percent)			1.10
Castle Creek Warrant \| Option Volatility \| Maximum
Asset Acquisition
Warrant measurement input (as a percent)			1.10
Castle Creek Warrant \| Risk Free Interest Rate \| Minimum
Asset Acquisition
Warrant measurement input (as a percent)			0.042
Castle Creek Warrant \| Risk Free Interest Rate \| Maximum
Asset Acquisition
Warrant measurement input (as a percent)			0.036
Arecor Limited
Asset Acquisition
Asset acquisition, consideration transferred	$ 7,000
Asset acquisition, deferred consideration payable	$ 1,000
Asset acquisition, deferred consideration, number of installments \| installment	2
Asset acquisition financial royalty assets	$ 800
Arecor Limited \| (AT229) Financial Royalty
Asset Acquisition
Asset acquisition financial royalty assets	1,900
Payment for contingent consideration liability, investing activities	3,000
Arecor Limited \| (AT220) Financial Royalty
Asset Acquisition
Asset acquisition financial royalty assets	$ 4,800