<SEC-DOCUMENT>0001470831-25-000187-index.html : 20250911
<SEC-HEADER>0001470831-25-000187.hdr.sgml : 20250911
<ACCEPTANCE-DATETIME>20250911174552
ACCESSION NUMBER:		0001470831-25-000187
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250909
FILED AS OF DATE:		20250911
DATE AS OF CHANGE:		20250911

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Accardi Mario Alberto
		CENTRAL INDEX KEY:			0002074392
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40445
		FILM NUMBER:		251309487

	MAIL ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		C/O CENTESSA PHARMACEUTICALS PLC
		STREET 2:		3RD FLOOR, 1 ASHLEY ROAD, ALTRINCHAM
		CITY:			CHESHIRE
		PROVINCE COUNTRY:   	X0
		ZIP:			WA14 2DT

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Centessa Pharmaceuticals plc
		CENTRAL INDEX KEY:			0001847903
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3RD FLOOR
		STREET 2:		1 ASHLEY ROAD
		CITY:			ALTRINCHAM, CHESHIRE
		STATE:			X0
		ZIP:			WA14 2DT
		BUSINESS PHONE:		44 7391 789784

	MAIL ADDRESS:	
		STREET 1:		3RD FLOOR
		STREET 2:		1 ASHLEY ROAD
		CITY:			ALTRINCHAM, CHESHIRE
		STATE:			X0
		ZIP:			WA14 2DT

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Centessa Pharmaceuticals Ltd
		DATE OF NAME CHANGE:	20210224
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>wk-form4_1757627149.xml
<DESCRIPTION>FORM 4
<TEXT>
Document 1 - file: wk-form4_1757627149.html

Document 1 - RAW XML: wk-form4_1757627149.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>centessasubstitutepoa.txt
<DESCRIPTION>EX-24.2 SUBSTITUTE POWER OF ATTORNEY
<TEXT>
Document 2 - file: centessasubstitutepoa.txt

</DOCUMENT>
</SEC-DOCUMENT>