<SEC-DOCUMENT>0001999371-25-005478-index.html : 20250506
<SEC-HEADER>0001999371-25-005478.hdr.sgml : 20250506
<ACCEPTANCE-DATETIME>20250506090014
ACCESSION NUMBER:		0001999371-25-005478
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		7
CONFORMED PERIOD OF REPORT:	20250620
FILED AS OF DATE:		20250506
DATE AS OF CHANGE:		20250506

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Centessa Pharmaceuticals plc
		CENTRAL INDEX KEY:			0001847903
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40445
		FILM NUMBER:		25915570

	BUSINESS ADDRESS:	
		STREET 1:		3RD FLOOR
		STREET 2:		1 ASHLEY ROAD
		CITY:			ALTRINCHAM, CHESHIRE
		STATE:			X0
		ZIP:			WA14 2DT
		BUSINESS PHONE:		44 7391 789784

	MAIL ADDRESS:	
		STREET 1:		3RD FLOOR
		STREET 2:		1 ASHLEY ROAD
		CITY:			ALTRINCHAM, CHESHIRE
		STATE:			X0
		ZIP:			WA14 2DT

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Centessa Pharmaceuticals Ltd
		DATE OF NAME CHANGE:	20210224
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>centessa_proxy-2025.htm
<DESCRIPTION>DEFINITIVE PROXY STATEMENT
<TEXT>
Document 1 - file: centessa_proxy-2025.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>centessa_proxy-2025img001.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: centessa_proxy-2025img001.gif

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>centessa_proxy-2025img002.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: centessa_proxy-2025img002.gif

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>centessa_proxy-2025img003.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: centessa_proxy-2025img003.gif

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>centessa_proxy-2025img004.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: centessa_proxy-2025img004.gif

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>proxy-1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: proxy-1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>proxy-2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: proxy-2.jpg

</DOCUMENT>
</SEC-DOCUMENT>