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Collaboration arrangements and concentration of credit risk - BMS (Details) $ in Thousands |  |  | 12 Months Ended |
--- | --- | --- | --- | ---
Jul. 31, 2015 USD ($) | May 21, 2015 USD ($) | Dec. 31, 2016 USD ($) item | Dec. 31, 2015 USD ($) | Dec. 31, 2014 USD ($) | Apr. 06, 2015 USD ($)
Collaboration arrangements |  |  |  |  |  |
License revenues |  |  | $ 975 |  |  |
Collaboration revenues |  |  | 7,164 |  |  |
Collaboration arrangement | BMS |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Fair value of derivative asset |  |  |  |  |  | $ 10,100
Collaborative revenue | BMS |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Collaboration revenues |  |  | $ 13,000 | $ 2,300 | $ 0 |
License revenue | BMS |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Number of potential targets included in collaborative agreement | item |  |  | 10 |  |  |
Deferred Revenue |  | $ 60,100 |  |  |  |
Up-front payment received |  | 50,000 |  |  |  |
Fair value of derivative asset |  | $ 10,100 |  |  |  |
Expected performance term (in years) |  |  | 19 years |  |  |
License revenues |  |  | $ 3,900 | $ 2,400 | $ 0 |
Royalty term after the first commercial sale |  |  | 10 years |  |  |
License revenue | BMS | Minimum |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Royalties percentage receivable |  |  | high single digit |  |  |
License revenue | BMS | Maximum |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Royalties percentage receivable |  |  | low double- digit |  |  |
License revenue | BMS | First Target Selection |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Milestone payments to be received upon achievement |  |  | $ 254,000 |  |  |
License revenue | BMS | Second, Third, and Fourth Targets Selection |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Target designation payment received | $ 15,000 |  |  |  |  |
License revenue | BMS | Fifth through Tenth Targets Selection |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Maximum target designation payments to which entitled per agreement |  |  | 16,500 |  |  |
License revenue | BMS | Other Selected Targets |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |
Milestone payments to be received upon achievement |  |  | $ 217,000 |  |  |

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- Definition Revenue earned during the period relating to collaboration arrangement. + References No definition available. + Details
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- Definition Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 13.A.3) -URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 13.A.4(a).Q1) -URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780 + Details
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- Definition Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.1(e)) -URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688 + Details
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