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Leases - Meibergdreef and Academisch Medisch Centrum ("AMC") campus, Amsterdam (Details) $ in Thousands | Dec. 31, 2016 USD ($) ft² facility | Apr. 30, 2015 ft² | Apr. 30, 2014 ft²
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Leases |  |  |
Future minimum lease payments | $ 39,355 |  |
Lease for facility from AMC located at Meibergdreef in Amsterdam, Netherlands |  |  |
Leases |  |  |
Number of facilities leased | facility | 2 |  |
Area of facility subject to lease (in square feet) | ft² | 26,000 |  |
Future minimum lease payments | $ 300 |  |
Lease for office facility from AMC located at AMC campus in Amsterdam, Netherlands |  |  |
Leases |  |  |
Area of facility subject to lease (in square feet) | ft² |  |  | 7,100
Future minimum lease payments | 200 |  |
Lease for laboratory facility from AMC located at AMC campus in Amsterdam, Netherlands | Jan Snel B.V. |  |  |
Leases |  |  |
Area of facility subject to lease (in square feet) | ft² |  | 9,300 |
Future minimum lease payments | $ 1,000 |  |

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- Definition Amount of required minimum rental payments for leases having an initial or remaining non-cancelable letter-terms in excess of one year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 10 -Section 55 -Paragraph 40 -Subparagraph (Note 3) -URI http://asc.fasb.org/extlink&oid=6584154&loc=d3e38371-112697 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 20 -Section 50 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6453985&loc=d3e41502-112717 + Details
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