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CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands | Dec. 31, 2016 | Dec. 31, 2015
--- | --- | ---
Current assets |  |
Cash and cash equivalents | $ 132,496 | $ 221,626
Accounts receivable and accrued income | 3,680 |
Accounts receivable and accrued income from related parties | 5,500 | 4,129
Inventories |  | 474
Prepaid expenses | 996 | 690
Other current assets | 1,274 | 1,194
Total current assets | 143,946 | 228,113
Non-current assets |  |
Property, plant and equipment, net | 35,702 | 26,011
Intangible assets, net | 8,324 | 6,815
Goodwill | 465 | 481
Other non-current assets | 1,828 | 1,243
Total non-current assets | 46,319 | 34,550
Total assets | 190,265 | 262,663
Current liabilities |  |
Accounts payable | 5,524 | 4,059
Accrued expenses and other current liabilities | 9,766 | 9,863
Current portion of long-term debt | 605 | 5,579
Current portion of deferred rent | 684 | 630
Current portion of deferred revenue | 6,142 | 6,778
Total current liabilities | 22,721 | 26,909
Non-current liabilities |  |
Long-term debt, net of current portion | 19,631 | 14,631
Deferred rent, net of current portion | 6,781 | 6,247
Deferred revenue, net of current portion | 75,612 | 83,445
Contingent consideration | 1,838 | 2,926
Other non-current liabilities | 51 | 578
Total non-current liabilities | 103,913 | 107,827
Total liabilities | 126,634 | 134,736
Commitments and contingencies (See Note 17) |  |
Shareholders' equity |  |
Ordinary shares, 0.05 par value: 60,000,000 shares authorized at December 31, 2016 and 2015 and 25,257,420 and 24,327,944 shares issued and outstanding at December 31, 2016 and 2015, respectively. | 1,593 | 1,542
Additional paid-in-capital | 464,653 | 455,897
Accumulated other comprehensive loss | (6,557) | (6,828)
Accumulated deficit | (396,058) | (322,684)
Total shareholders' equity | 63,631 | 127,927
Total liabilities and shareholders' equity | $ 190,265 | $ 262,663

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