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Fair value measurement - Changes in Level 3 Liabilities and Contingent Consideration (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Changes in Level 3 liabilities |  |  |
Beginning Balance | $ 3,763 | $ 2,018 | $ 299
Additions |  |  | 1,743
Issuance of financial instruments |  | (10,060) |
Allocation to shareholder's equity |  | 3,614 |
Gain (Loss) recorded due to changes in fair value of derivative liability | (1,865) | 8,501 | 181
Currency translation effects | 2 | (310) | (205)
Ending Balance | 1,900 | 3,763 | 2,018
Contingent consideration |  |  |
Changes in Level 3 liabilities |  |  |
Beginning Balance | 2,926 | 1,767 |
Additions |  |  | 1,743
Gain (Loss) recorded due to changes in fair value of derivative liability | (1,080) | 1,339 | 195
Currency translation effects | (8) | (180) | (171)
Ending Balance | $ 1,838 | 2,926 | 1,767
Contingent consideration | InoCard |  |  |
Contingent consideration |  |  |
Discount rate (as a percent) | 30.00% |  |
The number of months moving out of all milestones | 6 months |  |
Increase Probability of Success | 20.00% |  |
Decrease Probability Of Success | 20.00% |  |
Sensitivity down of the discount rate | 20.00% |  |
Sensitivity up of the discount rate | 40.00% |  |
Level 3 Derivative financial instruments |  |  |
Changes in Level 3 liabilities |  |  |
Beginning Balance | $ 837 | 251 | 299
Issuance of financial instruments |  | (10,060) |
Allocation to shareholder's equity |  | 3,614 |
Gain (Loss) recorded due to changes in fair value of derivative liability | (785) | 7,162 | (14)
Currency translation effects | 10 | (130) | (34)
Ending Balance | 62 | 837 | $ 251
Delay in milestones by 6 months | Contingent consideration | InoCard |  |  |
Contingent consideration |  |  |
Change in fair value | (209) | (313) |
Increasing the POS for the first milestone by 20% | Contingent consideration | InoCard |  |  |
Contingent consideration |  |  |
Change in fair value | 367 | 585 |
Decreasing the POS for the first milestone by 20% | Contingent consideration | InoCard |  |  |
Contingent consideration |  |  |
Change in fair value | (367) | (585) |
Reducing the discount rate from 30% to 20% | Contingent consideration | InoCard |  |  |
Contingent consideration |  |  |
Change in fair value | 638 | 1,228 |
Increasing the discount rate from 30% to 40% | Contingent consideration | InoCard |  |  |
Contingent consideration |  |  |
Change in fair value | $ (309) | $ (560) |

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- Definition Interest rate used to find the present value of an amount to be paid or received in the future as an input to measure fair value. For example, but not limited to, weighted average cost of capital (WACC), cost of capital, cost of equity and cost of debt. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (bbb) -URI http://asc.fasb.org/extlink&oid=66048111&loc=d3e19207-110258 + Details
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