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Intangible assets (Tables) | 12 Months Ended
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Dec. 31, 2016
Intangible assets |
Schedule of finite-lived intangible assets |
|  | December 31, 2016 |  | December 31, 2015 |
|  | Average remaining life |  | Historical costs |  | Accumulated amortization |  | Carrying amount |  | Historical costs |  | Accumulated amortization |  | Carrying amount |
|  | in thousands, except for average remaining life |
Licenses |  |  | 14.8 |  | $ | 7,799 |  | $ | (3,952 | ) | $ | 3,847 |  | $ | 5,730 |  | $ | (3,816 | ) | $ | 1,914 |
Acquired R&D |  |  | 17.3 |  |  | 4,908 |  |  | (431 | ) |  | 4,477 |  |  | 5,080 |  |  | (179 | ) |  | 4,901 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Total |  |  | 16.2 |  | $ | 12,707 |  | $ | (4,383 | ) | $ | 8,324 |  | $ | 10,810 |  | $ | (3,995 | ) | $ | 6,815 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Schedule of estimated future amortization expense |
Years |  | Amount |
|  | ($ in thousands) |
2017 |  | $ | 569 |
2018 |  |  | 566 |
2019 |  |  | 533 |
2020 |  |  | 513 |
2021 |  |  | 509 |
Thereafter |  |  | 5,634 |
​ | ​ | ​ | ​ | ​
Total |  | $ | 8,324 |
​ | ​ | ​ | ​ | ​
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Schedule of acquired licenses |
|  | December 31, 2016 |  | December 31, 2015 |
|  | in thousands |
National Institutes of Health |  | $ | 738 |  | $ | 866 |
St. Jude Children's Hospital |  |  | 659 |  |  | 723 |
Protein Sciences Corporation |  |  | 2,194 |  |  | 49 |
Other |  |  | 256 |  |  | 276 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Total |  | $ | 3,847 |  | $ | 1,914 |
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- Definition Tabular disclosure of the characteristics, including initial carrying value, residual amount, weighted average useful life, of finite-lived intangible assets acquired during the period by major class. A major class is composed of intangible assets that can be grouped together because they are similar, either by nature or by their use in the operations of the company. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275 + Details
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- Definition Tabular disclosure of assets, excluding financial assets and goodwill, lacking physical substance with a finite life, by either major class or business segment. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275 + Details
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