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Property, plant and equipment, net (Tables)

12 Months Ended

Dec. 31, 2016

Property, plant and equipment, net

Schedule of property, plant and equipment

		December 31, 2016			December 31, 2015
		in thousands
Leasehold improvements		$	30,582		$	18,343
Laboratory equipment			14,166			14,482
Office equipment			2,710			3,318
Construction-in-progress			313			804
​	​	​	​	​	​	​	​
Total property, plant, and equipment			47,771			36,947
Less accumulated depreciation			(12,069	)		(10,936	)
​	​	​	​	​	​	​	​
Property, plant and equipment, net		$	35,702		$	26,011
​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​

Summary of long-lived assets by geographic region

		December 31, 2016			December 31, 2015
		in thousands
Lexington, MA (US)		$	19,552		$	21,594
Europe			16,150			4,417
​	​	​	​	​	​	​	​
Total		$	35,702		$	26,011
​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​

X

- Definition

Tabular disclosure of long-lived assets, excluding financial instruments, long-term customer relationships of a financial institution, mortgage rights, deferred policy acquisition costs, and deferred tax assets, by geographic areas located in the entity's country of domicile and foreign countries in which the entity holds assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 41
-Subparagraph b
-URI http://asc.fasb.org/extlink&oid=68060357&loc=d3e9038-108599

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- References

No definition available.

+ Details

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X

- Definition

Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(13))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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