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Intangible assets (Tables)

12 Months Ended

Dec. 31, 2016

Intangible assets

Schedule of finite-lived intangible assets

December 31, 2016

December 31, 2015

Average remaining life

Historical costs

Accumulated amortization

Carrying amount

Historical costs

Accumulated amortization

Carrying amount

in thousands, except for average remaining life

Licenses

14.8

$

7,799

$

(3,952

)

$

3,847

$

5,730

$

(3,816

)

$

1,914

Acquired R&D

17.3

4,908

(431

)

4,477

5,080

(179

)

4,901

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Total

16.2

$

12,707

$

(4,383

)

$

8,324

$

10,810

$

(3,995

)

$

6,815

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Schedule of estimated future amortization expense

Years		Amount
		($ in thousands)
2017		$	569
2018			566
2019			533
2020			513
2021			509
Thereafter			5,634
​	​	​	​	​
Total		$	8,324
​	​	​	​	​
​	​	​	​	​

Schedule of acquired licenses

		December 31, 2016			December 31, 2015
		in thousands
National Institutes of Health		$	738		$	866
St. Jude Children's Hospital			659			723
Protein Sciences Corporation			2,194			49
Other			256			276
​	​	​	​	​	​	​	​
Total		$	3,847		$	1,914
​	​	​	​	​	​	​	​
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- References

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- Definition

Tabular disclosure of the characteristics, including initial carrying value, residual amount, weighted average useful life, of finite-lived intangible assets acquired during the period by major class. A major class is composed of intangible assets that can be grouped together because they are similar, either by nature or by their use in the operations of the company.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 1
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275

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- Definition

Tabular disclosure of assets, excluding financial assets and goodwill, lacking physical substance with a finite life, by either major class or business segment.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 1
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275

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- Definition

Tabular disclosure of the amount of amortization expense expected to be recorded in succeeding fiscal years for finite-lived intangible assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

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