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Fair value measurement - BMS collaboration (Details) - USD ($)
$ / shares in Units, $ in Thousands, shares in Millions
2 Months Ended 4 Months Ended 12 Months Ended
Aug. 07, 2015
Jun. 12, 2015
Jun. 12, 2015
Aug. 07, 2015
Dec. 31, 2016
Dec. 31, 2015
Apr. 06, 2015
Collaboration arrangements              
Proceeds from issuance of shares to collaboration partner           $ 75,493  
BMS Warrants              
Collaboration arrangements              
Sale of stock (in dollars per share) $ 29.67     $ 29.67      
Number of trading days used to calculate Volume Weighted Average Price ("VWAP")         20 days    
Number of days prior to purchase or exercise used to calculate Volume Weighted Average Price ("VWAP")         5 days    
Exercise price in respect of each warrant         $ 33.84    
Compounded annual growth rate used to determine fair value of exercise price         10.00%    
Gain (Loss) recorded due to changes in fair value of derivative asset     $ (7,300) $ (300)      
uniQure N.V. | Collaboration Agreement Approval ("First Closing") | BMS              
Collaboration arrangements              
Ownership percentage required per agreement         4.90%    
Sale of stock (in dollars per share)         $ 33.84    
uniQure N.V. | Selection Of Three Additional Collaboration Agreement Targets ("Second Closing") | BMS              
Collaboration arrangements              
Ownership percentage required per agreement         9.90%    
Sale of stock (in dollars per share) $ 29.67     $ 29.67      
Sale of stock - Percent of Volume Weighted Average Price ("VWAP")         110.00%    
Number of trading days used to calculate Volume Weighted Average Price ("VWAP")         20 days    
Number of days prior to purchase or exercise used to calculate Volume Weighted Average Price ("VWAP")         5 days    
uniQure N.V. | BMS Warrants | First Six New Targets Or Designation Of Sixth Target | BMS              
Collaboration arrangements              
Ownership percentage required per agreement         14.90%    
uniQure N.V. | BMS Warrants | First Nine New Targets Or Designation Of Ninth Target | BMS              
Collaboration arrangements              
Ownership percentage required per agreement         19.90%    
Collaboration arrangement | BMS              
Collaboration arrangements              
Fair value of derivative asset             $ 10,100
Number of shares issued to collaboration partner 1.3 1.1          
Proceeds from issuance of shares to collaboration partner $ 37,900 $ 37,600          
Extinguishment of derivative upon issuance of shares to collaboration partner 1,400 5,000          
Value of shares issued to collaboration partner $ 39,300 $ 32,600          
Market price per share $ 23.64 $ 29.37 $ 29.37 $ 23.64