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Share-based compensation - Compensation cost (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Share-based compensation
Share-based compensation expense	$ 6,214	$ 11,617	$ 8,396
Unrecognized compensation costs	$ 9,977
Weighted-average service period over which unrecognized compensation costs will be recognized	2 years 6 months 11 days
Research and development expenses
Share-based compensation
Share-based compensation expense	$ 3,972	8,591	6,563
Selling, general and administrative expense
Share-based compensation
Share-based compensation expense	2,242	3,026	1,833
Research and development, excluding 4D
Share-based compensation
Share-based compensation expense	3,302	2,162	2,476
Share options
Share-based compensation
Share-based compensation expense	5,187	10,469	7,966
Unrecognized compensation costs	$ 7,370
Weighted-average service period over which unrecognized compensation costs will be recognized	2 years 9 months 22 days
Restricted share units ("RSUs")
Share-based compensation
Share-based compensation expense	$ 528	$ 1,148	$ 430
Unrecognized compensation costs	$ 2,119
Weighted-average service period over which unrecognized compensation costs will be recognized	1 year 9 months 15 days
Performance share units ("PSUs")
Share-based compensation
Share-based compensation expense	$ 499
Unrecognized compensation costs	$ 488
Weighted-average service period over which unrecognized compensation costs will be recognized	1 year 5 months 23 days

X

- Definition

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB Topic 14.F)
-URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)(i)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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- Definition

Unrecognized cost of unvested share-based compensation awards.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (i)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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- Definition

Weighted average period over which unrecognized compensation is expected to be recognized for equity-based compensation plans, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (i)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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