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CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY - USD ($)
$ in Thousands
Common shares
BMS on June 12, 2015
Common shares
Additional paid-in capital
BMS on June 12, 2015
Additional paid-in capital
Accumulated other comprehensive income/(loss)
Accumulated deficit
BMS on June 12, 2015
Total
Beginning balance at Dec. 31, 2013   $ 798   $ 192,204 $ 115 $ (190,824)   $ 2,293
Beginning balance (in shares) at Dec. 31, 2013   12,194,906            
Increase (decrease) in shareholders' equity                
Loss for the period           (49,777)   (49,777)
Other comprehensive income/(loss)         (5,387)     (5,387)
Initial public / follow-on offering   $ 368   84,094       84,462
Initial public / follow-on offering (in shares)   5,400,000            
Shares issued as consideration in a business combination   $ 13   2,038       2,051
Shares issued as consideration in a business combination (in shares)   192,128            
Exercise of share options   $ 19   577       596
Exercise of share options (in shares)   305,160            
Share-based compensation expense       8,396       8,396
Ending balance at Dec. 31, 2014   $ 1,198   287,309 (5,272) (240,601)   42,634
Ending balance (in shares) at Dec. 31, 2014   18,092,194            
Increase (decrease) in shareholders' equity                
Loss for the period           (82,083)   (82,083)
Other comprehensive income/(loss)         (1,556)     (1,556)
Initial public / follow-on offering   $ 165   82,354       82,519
Initial public / follow-on offering (in shares)   3,000,000            
Issuance of shares to collaboration partner $ 132   $ 71,799       $ 71,931  
Issuance of shares to collaboration partner (in shares) 2,388,108              
Exercise of share options   $ 47   2,818       2,865
Exercise of share options (in shares)   847,642            
Share-based compensation expense       11,617       11,617
Ending balance at Dec. 31, 2015   $ 1,542   455,897 (6,828) (322,684)   $ 127,927
Ending balance (in shares) at Dec. 31, 2015   24,327,944           24,327,944
Increase (decrease) in shareholders' equity                
Loss for the period           (73,374)   $ (73,374)
Other comprehensive income/(loss)         271     271
Exercise of share options   $ 41   2,542       2,583
Exercise of share options (in shares)   750,408            
Restricted share units distributed during the period   $ 10           10
Restricted share units distributed during the period (in shares)   179,068            
Share-based compensation expense       6,214       6,214
Ending balance at Dec. 31, 2016   $ 1,593   $ 464,653 $ (6,557) $ (396,058)   $ 63,631
Ending balance (in shares) at Dec. 31, 2016   25,257,420           25,257,420