12Leases

The Company leases various office space and laboratory space under operating lease agreements, expiring at various dates through 2032. These leases are described in more detail below.

Rent expense for the three months ended March 31, 2017, was $1.0 million and $0.8 million in the same period 2016. Rent expense is calculated on a straight-line basis over the term of the leases, and takes into account $11.8 million of lease incentives received.

Aggregate minimum lease payments for the calendar years ending December 31, 2017, 2018, 2019, 2020 and 2021 and beyond at March 31, 2017 were as follows:

	in thousands
2017 (nine months remaining)	$	1,746
2018	4,132
2019	3,675
2020	3,729
2021 and beyond	26,400

Total minimum lease payments	$	39,682

Lexington, Massachusetts

In July 2013, uniQure entered into a lease for a facility in Lexington, Massachusetts, United States. The term of the lease commenced in November 2013 and was set for 10 years and is non-cancellable. The lease for this facility terminates in 2024, and subject to the provisions of the lease, may be renewed for two subsequent five-year terms. The Company expects to complete the qualification of its approximately 53,000 square feet manufacturing facility in 2017. The future aggregate minimum lease payments under the non-cancellable term of the lease amount to $14.0 million. As of March 31, 2017, the Company recorded a total deferred rent of $6.1 million (December 31, 2016: $6.2 million), with a current element of $0.7 million (December 31, 2016: $0.7 million) related to lease incentives received. The lease provides for annual minimum increases in rent, based on a consumer price index.

Paasheuvelweg, Amsterdam

In March 2016, the Company entered into a 16-year lease for a facility in Amsterdam, the Netherlands, and amended this agreement in June 2016. The Company expects to consolidate its three Amsterdam sites into the new site by the end of May 2017. The lease for this facility terminates in 2032, with an option to extend for further periods of five years. Following the completion of its restructuring by the end of 2017, the Company will seek to sublease parts of the facility. The future aggregate minimum lease payments under the non-cancellable term of the lease amount to $24.8 million. The lease contract provides for annual minimum increases in rent, based on a consumer price index.

Meibergdreef, Amsterdam

In April 2015, uniQure entered into a lease with Jan Snel B.V. for a laboratory facility of approximately 9,300 square feet, located at the Meibergdreef in Amsterdam, the Netherlands. The minimum lease period terminates in September 2018. The future aggregate minimum lease payments under the non-cancellable term of the lease amount to $0.9 million.