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Fair value measurement - Changes in Level 3 Liabilities and Contingent Consideration (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2016
Changes in Level 3 liabilities      
Beginning Balance $ 1,900 $ 3,763 $ 3,763
(Gain) Loss recorded due to changes in fair value of derivative liability 95 (257)  
Currency translation effects 28 157  
Ending Balance 2,023 3,663 1,900
Contingent consideration      
Changes in Level 3 liabilities      
Beginning Balance 1,838 2,926 2,926
(Gain) Loss recorded due to changes in fair value of derivative liability 124 60  
Currency translation effects 27 127  
Ending Balance $ 1,989 3,113 $ 1,838
Contingent consideration | InoCard      
Contingent consideration      
Discount rate (as a percent)     30.00%
The number of months moving out of all milestones 6 months    
Increase Probability of Success 20.00%    
Decrease Probability Of Success 20.00%    
Sensitivity down of the discount rate 20.00%    
Sensitivity up of the discount rate 40.00%    
Level 3 Derivative financial instruments      
Changes in Level 3 liabilities      
Beginning Balance $ 62 837 $ 837
(Gain) Loss recorded due to changes in fair value of derivative liability (29) (317)  
Currency translation effects 1 30  
Ending Balance 34 $ 550 62
Delay in milestones by 6 months | Contingent consideration | InoCard      
Contingent consideration      
Change in fair value (226)   (209)
Increasing the POS for the first milestone by 20% | Contingent consideration | InoCard      
Contingent consideration      
Change in fair value 398   367
Decreasing the POS for the first milestone by 20% | Contingent consideration | InoCard      
Contingent consideration      
Change in fair value (398)   (367)
Reducing the discount rate from 30% to 20% | Contingent consideration | InoCard      
Contingent consideration      
Change in fair value 636   638
Increasing the discount rate from 30% to 40% | Contingent consideration | InoCard      
Contingent consideration      
Change in fair value $ (305)   $ (309)