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Share-based compensation - Compensation cost (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2017 | Sep. 30, 2016 | Sep. 30, 2017 | Sep. 30, 2016
Share-based compensation |  |  |  |
Share-based compensation expense | $ 2,447 | $ 923 | $ 5,978 | $ 5,020
Unrecognized compensation costs | 14,791 |  | $ 14,791 |
Weighted-average remaining period for recognition (in years) |  |  | 2 years 1 month 10 days |
Research and development expenses | Employees |  |  |  |
Share-based compensation |  |  |  |
Share-based compensation expense | 1,131 | 893 | $ 2,612 | 2,670
Research and development expenses | Non-employees |  |  |  |
Share-based compensation |  |  |  |
Share-based compensation expense |  |  |  | 670
Selling, general and administrative expense | Employees |  |  |  |
Share-based compensation |  |  |  |
Share-based compensation expense | 1,316 | 30 | 3,366 | 1,680
Share options |  |  |  |
Share-based compensation |  |  |  |
Share-based compensation expense | 638 | 718 | 2,347 | 4,408
Unrecognized compensation costs | 7,041 |  | $ 7,041 |
Weighted-average remaining period for recognition (in years) |  |  | 2 years 6 months 7 days |
Restricted share units ("RSUs") |  |  |  |
Share-based compensation |  |  |  |
Share-based compensation expense | 728 | 88 | $ 1,960 | 323
Unrecognized compensation costs | 4,003 |  | $ 4,003 |
Weighted-average remaining period for recognition (in years) |  |  | 1 year 7 months 21 days |
Performance share units ("PSUs") |  |  |  |
Share-based compensation |  |  |  |
Share-based compensation expense | 1,081 | $ 117 | $ 1,671 | $ 289
Unrecognized compensation costs | $ 3,747 |  | $ 3,747 |
Weighted-average remaining period for recognition (in years) |  |  | 1 year 10 months 2 days |

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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Unrecognized cost of unvested share-based compensation awards. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Weighted average period over which unrecognized compensation is expected to be recognized for equity-based compensation plans, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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