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Collaboration arrangements and concentration of credit risk - Revenues from and amounts owed with collaboration partners (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2017 | Sep. 30, 2016 | Sep. 30, 2017 | Sep. 30, 2016 | Dec. 31, 2016
Collaboration arrangements |  |  |  |  |
Revenues | $ 2,260 | $ 7,221 | $ 10,523 | $ 15,967 |
Collaboration arrangement |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Revenues | 2,260 | 7,221 | 10,523 | 15,967 |
Amounts owed from partners in relation to the collaboration | 1,945 |  | 1,945 |  | $ 9,180
Collaboration arrangement | BMS |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Revenues | 2,260 | 5,125 | 5,877 | 10,396 |
Amounts owed from partners in relation to the collaboration | $ 1,945 |  | 1,945 |  | 5,500
Collaboration arrangement | Chiesi Pharmaceutical |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Revenues |  | $ 2,096 | $ 4,646 | $ 5,571 |
Amounts owed from partners in relation to the collaboration |  |  |  |  | $ 3,680

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