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Collaboration arrangements and concentration of credit risk - Amounts owed by BMS (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
May 31, 2015 item | Jun. 30, 2019 USD ($) shares | Jun. 30, 2018 USD ($) | Jun. 30, 2019 USD ($) item shares | Jun. 30, 2018 USD ($) | Dec. 31, 2018 USD ($) shares
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |
Common Stock, Shares, Outstanding | shares |  | 37,839,833 |  | 37,839,833 |  | 37,351,653
Total revenues |  | $ 2,474 | $ 3,050 | $ 3,610 | $ 6,528 |
Amounts owed in relation to the collaboration services |  | 355 |  | 355 |  | $ 233
BMS arrangement |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |
Total revenues |  |  |  | 355 |  | 233
BMS arrangement | Bristol Myers Squibb |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |
Number of collaboration targets | item | 4 |  |  |  |  |
Amounts owed in relation to the collaboration services |  | $ 355 |  | $ 355 |  | $ 233
BMS arrangement | Maximum | Bristol Myers Squibb |  |  |  |  |  |
Revenue, Initial Application Period Cumulative Effect Transition [Line Items] |  |  |  |  |  |
Number of collaboration targets | item |  |  |  | 10 |  |

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