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v3.19.2

CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY - USD ($) $ in Thousands | Ordinary shares | Additional paid-in capital | Accumulated other comprehensive (loss)/income | Accumulated deficit | Total
--- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2017 | $ 1,947 | $ 566,530 | $ (3,800) | $ (475,318) | $ 89,359
Beginning balance (in shares) at Dec. 31, 2017 | 31,339,040 |  |  |  |
Increase (decrease) in shareholders' equity |  |  |  |  |
Cumulative effect of retroactive implementation of ASC 606 Revenue recognition |  |  | 1,802 | 23,116 | 24,918
Loss for the period |  |  |  | (39,381) | (39,381)
Other comprehensive loss |  |  | (2,690) |  | (2,690)
Follow-on public offering | $ 309 | 138,182 |  |  | 138,491
Follow-on public offering (in shares) | 5,175,000 |  |  |  |
Exercise of share options | $ 12 | 2,975 |  |  | 2,987
Exercise of share options (in shares) | 267,753 |  |  |  |
Restricted and performance share units distributed during the period | $ 20 | (20) |  |  |
Restricted and performance share units distributed during the period (in shares) | 344,948 |  |  |  |
Share-based compensation expense |  | 4,732 |  |  | 4,732
Ending balance at Jun. 30, 2018 | $ 2,288 | 712,399 | (4,688) | (491,583) | 218,416
Ending balance (in shares) at Jun. 30, 2018 | 37,126,741 |  |  |  |
Beginning balance at Mar. 31, 2018 | $ 1,971 | 570,595 | (1,312) | (470,991) | 100,263
Beginning balance (in shares) at Mar. 31, 2018 | 31,771,816 |  |  |  |
Increase (decrease) in shareholders' equity |  |  |  |  |
Loss for the period |  |  |  | (20,592) | (20,592)
Other comprehensive loss |  |  | (3,376) |  | (3,376)
Follow-on public offering | $ 309 | 138,182 |  |  | 138,491
Follow-on public offering (in shares) | 5,175,000 |  |  |  |
Exercise of share options | $ 5 | 1,420 |  |  | 1,425
Exercise of share options (in shares) | 121,592 |  |  |  |
Restricted and performance share units distributed during the period | $ 3 | (3) |  |  |
Restricted and performance share units distributed during the period (in shares) | 58,333 |  |  |  |
Share-based compensation expense |  | 2,205 |  |  | 2,205
Ending balance at Jun. 30, 2018 | $ 2,288 | 712,399 | (4,688) | (491,583) | 218,416
Ending balance (in shares) at Jun. 30, 2018 | 37,126,741 |  |  |  |
Beginning balance at Dec. 31, 2018 | $ 2,299 | 720,072 | (7,259) | (535,506) | $ 179,606
Beginning balance (in shares) at Dec. 31, 2018 | 37,351,653 |  |  |  | 37,351,653
Increase (decrease) in shareholders' equity |  |  |  |  |
Loss for the period |  |  |  | (59,171) | $ (59,171)
Other comprehensive loss |  |  | (1,259) |  | (1,259)
Hercules warrants exercise | $ 2 | 1,271 |  |  | 1,273
Hercules warrants exercise (in shares) | 37,175 |  |  |  |
Exercise of share options | $ 14 | 2,542 |  |  | 2,556
Exercise of share options (in shares) | 236,654 |  |  |  |
Restricted and performance share units distributed during the period | $ 12 | (12) |  |  |
Restricted and performance share units distributed during the period (in shares) | 209,481 |  |  |  |
Share-based compensation expense |  | 8,886 |  |  | 8,886
Issuance of ordinary shares relating to employee stock purchase plan |  | 165 |  |  | 165
Issuance of ordinary shares relating to employee stock purchase plan (in shares) | 4,870 |  |  |  |
Ending balance at Jun. 30, 2019 | $ 2,327 | 732,924 | (8,518) | (594,677) | $ 132,056
Ending balance (in shares) at Jun. 30, 2019 | 37,839,833 |  |  |  | 37,839,833
Beginning balance at Mar. 31, 2019 | $ 2,322 | 727,795 | (9,727) | (563,278) | $ 157,112
Beginning balance (in shares) at Mar. 31, 2019 | 37,763,842 |  |  |  |
Increase (decrease) in shareholders' equity |  |  |  |  |
Loss for the period |  |  |  | (31,399) | (31,399)
Other comprehensive loss |  |  | 1,209 |  | 1,209
Exercise of share options | $ 4 | 454 |  |  | 458
Exercise of share options (in shares) | 52,847 |  |  |  |
Restricted and performance share units distributed during the period | $ 1 | (1) |  |  |
Restricted and performance share units distributed during the period (in shares) | 21,400 |  |  |  |
Share-based compensation expense |  | 4,592 |  |  | 4,592
Issuance of ordinary shares relating to employee stock purchase plan |  | 84 |  |  | 84
Issuance of ordinary shares relating to employee stock purchase plan (in shares) | 1,744 |  |  |  |
Ending balance at Jun. 30, 2019 | $ 2,327 | $ 732,924 | $ (8,518) | $ (594,677) | $ 132,056
Ending balance (in shares) at Jun. 30, 2019 | 37,839,833 |  |  |  | 37,839,833

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