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Share-based compensation - Summary of share-based compensation expense and unrecognized costs (Details) - 2014 Plan - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2021 | Jun. 30, 2020 | Jun. 30, 2021 | Jun. 30, 2020 | Dec. 31, 2020
Share-based compensation |  |  |  |  |
Authorized shares | 12,601,471 |  | 12,601,471 |  |
Increase in authorized shares |  |  | 4,000,000 |  |
Share-based compensation expense | $ 7,021 | $ 5,714 | $ 12,775 | $ 10,054 |
Unrecognized compensation costs | 60,607 |  | $ 60,607 |  |
Weighted-average remaining period for recognition (in years) |  |  | 2 years 7 months 28 days |  |
Research and development expenses |  |  |  |  |
Share-based compensation |  |  |  |  |
Share-based compensation expense | 3,286 | 2,889 | $ 5,960 | 5,271 |
Selling, general and administrative expense |  |  |  |  |
Share-based compensation |  |  |  |  |
Share-based compensation expense | 3,735 | 2,825 | 6,815 | 4,783 |
Share options |  |  |  |  |
Share-based compensation |  |  |  |  |
Share-based compensation expense | $ 3,350 | 2,746 | $ 6,190 | 4,954 |
Outstanding of fully vested share options | 3,417,931 |  | 3,417,931 |  | 2,659,279
Unrecognized compensation costs | $ 34,855 |  | $ 34,855 |  |
Weighted-average remaining period for recognition (in years) |  |  | 2 years 11 months 26 days |  |
Restricted share units ("RSUs") |  |  |  |  |
Share-based compensation |  |  |  |  |
Share-based compensation expense | 3,222 | 2,209 | $ 5,782 | 3,653 |
Unrecognized compensation costs | 24,960 |  | $ 24,960 |  |
Weighted-average remaining period for recognition (in years) |  |  | 2 years 3 months |  |
Performance share units ("PSUs") |  |  |  |  |
Share-based compensation |  |  |  |  |
Share-based compensation expense | 449 | $ 759 | $ 803 | $ 1,447 |
Unrecognized compensation costs | $ 792 |  | $ 792 |  |
Weighted-average remaining period for recognition (in years) |  |  | 6 months 29 days |  |

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Amount of cost not yet recognized for nonvested award under share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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