XML 41 R30.htm IDEA: XBRL DOCUMENT
v3.21.2

Collaboration arrangements and concentration of credit risk - BMS collaboration - Narrative (Details) $ in Thousands |  |  |  | 3 Months Ended | 9 Months Ended |
--- | --- | --- | --- | --- | --- | ---
Jun. 24, 2021 USD ($) | Dec. 01, 2020 USD ($) item | Jun. 24, 2020 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2020 USD ($) | Sep. 30, 2021 USD ($) item | Sep. 30, 2020 USD ($) | Dec. 31, 2020 USD ($)
Collaboration arrangements |  |  |  |  |  |  |  |
Number of collaboration targets | item |  |  |  |  |  | 4 |  |
Revenue |  |  |  | $ 1,989 | $ 1,789 | $ 466,311 | $ 3,428 |
Accounts receivable |  |  |  | $ 3,771 |  | $ 3,771 |  | $ 6,618
Enacted tax rate |  |  |  | 25.00% |  | 25.00% |  |
Tax benefit past share issuance cost |  |  |  | $ 0 |  | $ 2,977 |  |
CSL Behring collaboration |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Revenue |  |  |  | 0 | 0 | 462,400 | 0 |
Upfront cash to receive upon the closing of the agreement | $ 450,000 |  | $ 450,000 |  |  |  |  |
Other payments received | $ 12,400 |  |  |  |  |  |  |
Accounts receivable |  |  |  | 1,900 |  | 1,900 |  | $ 2,100
Regulatory and commercial milestone payments received |  |  | $ 1,600,000 |  |  |  |  |
License revenues from related party |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Revenue |  |  |  |  | 1,776 |  | 3,353 |
Collaboration revenues from related party |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Revenue |  |  |  |  | 13 |  | 75 |
Collaboration revenues |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Revenue |  |  |  | 1,989 |  | 3,911 |  |
Collaboration revenues | CSL Behring collaboration |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Revenue |  |  |  | 500 | $ 0 | $ 900 | $ 0 |
BMS arrangement | Bristol Myers Squibb |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Initial research term |  |  |  |  |  | 4 years |  |
Number of collaboration targets | item |  | 4 |  |  |  |  |  |
Collaboration Agreement, Threshold Number Of Collaboration Targets That Can Be Replaced | item |  | 2 |  |  |  |  |  |
Threshold Number Of New Collaboration Targets In The Field Of Cardiovascular Disease | item |  | 2 |  |  |  |  |  |
License revenue | Bristol Myers Squibb |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Revenue |  |  |  | $ 0 |  | $ 0 |  |
Bristol Myers Squibb | BMS arrangement |  |  |  |  |  |  |  |
Collaboration arrangements |  |  |  |  |  |  |  |
Collaboration Agreement, Threshold Research, Development And Regulatory Milestone Payments Receivable |  | $ 217,000 |  |  |  |  |  |

X
- Definition Amount of increase in additional paid in capital (APIC) resulting from tax effect of prior years issuance costs. + References No definition available. + Details
Name: | qure_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCostsTaxEffectPriorYears
Namespace Prefix: | qure_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition The amount of other payments related to transfer of license received as of the effective date of the collaboration agreement + References No definition available. + Details
Name: | qure_CollaborationAgreementOtherPaymentsReceived
Namespace Prefix: | qure_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Represents the threshold number of collaboration targets that can be replaced under the collaboration agreement. + References No definition available. + Details
Name: | qure_CollaborationAgreementThresholdNumberOfCollaborationTargetsThatCanBeReplaced
Namespace Prefix: | qure_
Data Type: | xbrli:integerItemType
Balance Type: | na
Period Type: | duration

X
- Definition The amount of threshold research, development and regulatory payment receivable under the collaboration agreement. + References No definition available. + Details
Name: | qure_CollaborationAgreementThresholdResearchDevelopmentAndRegulatoryMilestonePaymentsReceivable
Namespace Prefix: | qure_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

X
- Definition Initial research term. + References No definition available. + Details
Name: | qure_InitialResearchTerm
Namespace Prefix: | qure_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | duration

X
- Definition The number of collaboration targets. + References No definition available. + Details
Name: | qure_NumberOfCollaborationTargets
Namespace Prefix: | qure_
Data Type: | xbrli:decimalItemType
Balance Type: | na
Period Type: | duration

X
- Definition The amount of regulatory and commercial milestone payments to be received. + References No definition available. + Details
Name: | qure_RegulatoryAndCommercialMilestonePaymentsReceivable
Namespace Prefix: | qure_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

X
- Definition Represents the threshold number of new collaboration targets in the field of cardiovascular disease under the collaboration agreement. + References No definition available. + Details
Name: | qure_ThresholdNumberOfNewCollaborationTargetsInFieldOfCardiovascularDisease
Namespace Prefix: | qure_
Data Type: | xbrli:integerItemType
Balance Type: | na
Period Type: | duration

X
- Definition Upfront cash to receive upon the closing of the agreement. + References No definition available. + Details
Name: | qure_UpfrontCashToReceiveUponClosingOfAgreement
Namespace Prefix: | qure_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Amount, after allowance for credit loss, of right to consideration from customer for product sold and service rendered in normal course of business, classified as current. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section 45 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=121593590&loc=d3e4428-111522 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(3)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 3: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=121566466&loc=d3e6676-107765 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section 45 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=121593590&loc=d3e4531-111522 + Details
Name: | us-gaap_AccountsReceivableNetCurrent
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

X
- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
Name: | us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Percentage of domestic federal statutory tax rate applicable to pretax income (loss). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 6.I.Fact.4) -URI http://asc.fasb.org/extlink&oid=116825942&loc=d3e330036-122817 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32687-109319 + Details
Name: | us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
Namespace Prefix: | us-gaap_
Data Type: | num:percentItemType
Balance Type: | na
Period Type: | duration

X
- Definition Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 41 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e9038-108599 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=121604090&loc=SL49130545-203045 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8933-108599 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 32 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8933-108599 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8906-108599 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8736-108599 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8736-108599 Reference 8: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 4 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121604090&loc=SL49130543-203045 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 42 -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e9054-108599 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 40 -URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e9031-108599 Reference 11: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 924 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 11.L) -URI http://asc.fasb.org/extlink&oid=6472922&loc=d3e499488-122856 + Details
Name: | us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Details
Name: | srt_CounterpartyNameAxis=qure_CslBehringCollaborationMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | srt_ProductOrServiceAxis=qure_LicenseRevenueFromRelatedPartyMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | srt_ProductOrServiceAxis=qure_CollaborativeRevenueFromRelatedPartyMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | srt_ProductOrServiceAxis=qure_CollaborativeRevenueMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_TypeOfArrangementAxis=us-gaap_CollaborativeArrangementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | srt_CounterpartyNameAxis=qure_BristolMyersSquibbMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_TypeOfArrangementAxis=qure_CollaborativeArrangementLicenseRevenueMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | dei_LegalEntityAxis=qure_BristolMyersSquibbMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |