The amount of consideration payable in development milestones through Phase I or II as at the date of acquisition.

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The amount of consideration payable in development milestones through Phase III as at the date of acquisition.

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The amount of liability related to mandatory redeemable shares as at the date of acquisition.

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Number of employees employed by acquiree as at the date of acquisition.

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Number of licenses continue to collaborate as at the date of acquisition.

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Fair value of contingent consideration in a business combination that is classified in other non-current liabilities.

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The amount of increase or decrease in fair market value of contingent consideration.

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The provisional fair value of intangible asset as at the end of the reporting period.

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Percentage of increase in Probability of Success in clinical development.

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Percentage of milestones payable through the issuance of shares.

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The percentage of weighted average cost of capital.

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Term of reduction in achieving milestones.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Percentage of voting equity interests acquired at the acquisition date in the business combination.

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Amount of equity interests of the acquirer, including instruments or interests issued or issuable in consideration for the business combination.

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Amount of liability recognized arising from contingent consideration in a business combination, expected to be settled beyond one year or the normal operating cycle, if longer.

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Amount of deferred tax asset attributable to deductible temporary differences and carryforwards acquired at the acquisition date.

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Amount of deferred tax liability attributable to taxable temporary differences assumed at the acquisition date.

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Amount of deferred tax liability attributable to taxable temporary differences from intangible assets other than goodwill.

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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Corlieve transaction - Narrative (Details) € in Thousands, $ in Thousands			3 Months Ended	9 Months Ended
	Jul. 30, 2021 USD ($) Institution employee	Jul. 30, 2021 EUR (€)	Sep. 30, 2021 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2021 EUR (€)	Sep. 30, 2021 EUR (€)	Jul. 30, 2021 EUR (€) Institution employee	Dec. 31, 2020 USD ($)
Business Acquisition [Line Items]
Contingent consideration			$ 23,781	$ 23,781
Enacted tax rate			25.00%	25.00%	25.00%
Goodwill			$ 28,060	$ 28,060				$ 542
Repayment of debt acquired through acquisition of Corlieve				1,175
Acquired research & development
Business Acquisition [Line Items]
Acquired in-process research and development intangible asset			61,734	61,734
Acquisition of Corlieve
Business Acquisition [Line Items]
Number of institutions \| Institution	2						2
Number of employees employed \| employee	7						7
Percentage of outstanding ordinary shares	97.70%						97.70%
Value of shares issued	$ 53,300	€ 44,900
Amount of liability related to mandatorily redeemable shares	900						€ 700
Contingent consideration	$ 23,950		23,781	23,781			€ 20,200
Fair value of contingent consideration			23,800	23,800		€ 20,500
Weighted average cost of capital	10.40%						10.40%
Provisional fair value of IPR&D intangible asset	$ 63,300						€ 53,300
Deferred tax assets	2,200						1,800
Intangible assets	$ 15,800						13,300
Enacted tax rate	25.00%	25.00%
Deferred tax liability, net	$ 13,600						11,500
Goodwill	28,200						23,770
Repayment of debt acquired through acquisition of Corlieve				$ 1,200	€ 1,000
Acquisition of Corlieve \| Maximum
Business Acquisition [Line Items]
Consideration payable in development milestones through phase I or II	42,500						35,800
Consideration payable in development milestones through phase III	$ 169,900						€ 143,100
Percentage of milestones payable through the issuance of shares	25.00%	25.00%
Acquisition of Corlieve \| Increase Probability of Success
Business Acquisition [Line Items]
Percentage of increase in Probability of Success	5.00%	5.00%		5.00%	5.00%
Increase in fair market of contingent consideration	$ 1,900			$ 1,900
Fair value of contingent consideration	25,900		25,700	25,700
Acquisition of Corlieve \| Reduction in the estimated timing of achieving such milestones
Business Acquisition [Line Items]
Increase in fair market of contingent consideration	1,300			1,300
Fair value of contingent consideration	$ 25,300		$ 25,100	$ 25,100
Term of reduction in achieving milestones	6 months	6 months		6 months	6 months