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Fair value measurement - Contingent Consideration (Details)
$ in Thousands, € in Millions
 2 Months Ended 9 Months Ended
Jul. 30, 2021
USD ($)
Jul. 30, 2021
EUR (€)
Sep. 30, 2021
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2021
EUR (€)
Jul. 30, 2021
EUR (€)
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]            
Contingent consideration     $ 23,781 $ 23,781    
Balance at September 30, 2021     23,781 23,781    
Acquisition of Corlieve            
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]            
Contingent consideration $ 23,950   23,781 23,781   € 20.2
Fair value of contingent consideration     23,800 23,800 € 20.5  
Amount recorded on Acquisition Date     23,950      
Change in fair value (included within research and development expenses)     416      
Currency translation effects     (585)      
Balance at September 30, 2021 23,950 € 20.2 23,781 $ 23,781    
Acquisition of Corlieve | Maximum            
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]            
Contingent consideration payable upon achievement of contractually defined milestones $ 212,400         € 178.8
Acquisition of Corlieve | Increase Probability of Success            
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]            
Percentage of increase in Probability of Success 5.00% 5.00%   5.00%    
Increase in fair market of contingent consideration $ 1,900     $ 1,900    
Fair value of contingent consideration 25,900   25,700 25,700    
Acquisition of Corlieve | Reduction in the estimated timing of achieving such milestones            
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]            
Increase in fair market of contingent consideration 1,300     1,300    
Fair value of contingent consideration $ 25,300   $ 25,100 $ 25,100    
Term of reduction in achieving milestones 6 months 6 months   6 months