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Shareholders' equity (Details) - USD ($) $ / shares in Units, $ in Thousands		2 Months Ended	3 Months Ended	9 Months Ended
	Mar. 01, 2021	Apr. 30, 2021	Sep. 30, 2021	Sep. 30, 2021
Aggregate offering price				$ 29,565
Tax benefit past share issuance cost			$ 0	2,977
Sales Agreement with SVB Leerink LLC
Percentage of gross proceeds	3.00%
Net proceeds		$ 29,600
Sales Agreement with SVB Leerink LLC | Direct Incremental Labor
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs			$ 0	$ 1,300
Sales Agreement with SVB Leerink LLC | Ordinary shares
Shares issued in connection with offering		921,730
Share price (in dollars per share)		$ 33.52
Sales Agreement with SVB Leerink LLC | Maximum
Aggregate offering price	$ 200,000

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