<SEC-DOCUMENT>0000904454-21-000535.txt : 20210617
<SEC-HEADER>0000904454-21-000535.hdr.sgml : 20210617
<ACCEPTANCE-DATETIME>20210617094931
ACCESSION NUMBER:		0000904454-21-000535
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20210615
FILED AS OF DATE:		20210617
DATE AS OF CHANGE:		20210617

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CALOZ PIERRE
		CENTRAL INDEX KEY:			0001867944

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36294
		FILM NUMBER:		211023575

	MAIL ADDRESS:	
		STREET 1:		UNIQURE N.V.
		STREET 2:		PAASHEUVELWEG 25A
		CITY:			AMSTERDAM
		STATE:			P7
		ZIP:			P7 11058BP

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			uniQure N.V.
		CENTRAL INDEX KEY:			0001590560
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		PAASHEUVELWEG 25A
		CITY:			AMSTERDAM
		STATE:			P7
		ZIP:			1105 BP
		BUSINESS PHONE:		1-339-970-7000

	MAIL ADDRESS:	
		STREET 1:		PAASHEUVELWEG 25A
		CITY:			AMSTERDAM
		STATE:			P7
		ZIP:			1105 BP

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	uniQure B.V.
		DATE OF NAME CHANGE:	20131030
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2021-06-15</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001590560</issuerCik>
        <issuerName>uniQure N.V.</issuerName>
        <issuerTradingSymbol>QURE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001867944</rptOwnerCik>
            <rptOwnerName>CALOZ PIERRE</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O UNIQURE N.V.</rptOwnerStreet1>
            <rptOwnerStreet2>PAASHEUVELWEG 25A</rptOwnerStreet2>
            <rptOwnerCity>AMSTERDAM</rptOwnerCity>
            <rptOwnerState>P7</rptOwnerState>
            <rptOwnerZipCode>1105BP</rptOwnerZipCode>
            <rptOwnerStateDescription>NETHERLANDS</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Operating Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <remarks>No securities beneficially owned.

Exhibit List: Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Christian Klemt, Attorney-in-Fact</signatureName>
        <signatureDate>2021-06-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>uniqurepoa_060721.htm
<DESCRIPTION>EXHIBIT 24 TO FORM 3 FOR PIERRE CALOZ
<TEXT>
<html>
  <head>
    <title></title>
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         Copyright 1995 - 2021 Broadridge -->
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  <div>
    <div style="text-align: center;">EXHIBIT 24 TO FORM 3<br>
    </div>
    <div style="text-align: center;">POWER OF ATTORNEY</div>
    <div><br>
    </div>
    <div style="text-align: justify;">I hereby constitute and appoint each of David Cerveny and Christian Klemt, signing singly, my true and lawful attorney-in-fact to:</div>
    <div><br>
    </div>
    <div style="text-align: justify;">(1) execute on my behalf any Form 3-Initial Statement of Beneficial Ownership of Securities, Form 4-Statement of Changes of Beneficial Ownership of Securities, or Form 5-Annual Statement of Beneficial Ownership of
      Securities, including any amendments, supplements or exhibits thereto (each, a "Section 16 Report"), which I am required to file in my capacity as an officer, director or owner of greater than 10% of the outstanding shares of uniQure N.V. (the
      "Company") in accordance with Section 16(a) of the Securities Exchange Act of 1934, as amended (the</div>
    <div style="text-align: justify;">"Act") and the rules thereunder;</div>
    <div><br>
    </div>
    <div style="text-align: justify;">(2) do and perform any and all acts for and on my behalf that may be necessary or desirable to complete and execute any Section 16 Report and timely file such report with the United States Securities and Exchange
      Commission and any stock exchange or similar authority;</div>
    <div><br>
    </div>
    <div style="text-align: justify;">(3) seek or obtain, as my representative and on my behalf, information on transactions in the Company's securities from any third party, including brokers, employee benefit plan administrators and trustees, and I
      hereby authorize any such third party to release any such information to each of my attorneys-in-fact appointed by this Power of Attorney; and</div>
    <div><br>
    </div>
    <div style="text-align: justify;">(4) take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be to my benefit, in my best interest, or that I am legally required to do, it being
      understood that the documents executed by such attorney-in-fact on my behalf pursuant to this Power of Attorney shall be in such form and shall contain such terms and</div>
    <div style="text-align: justify;">conditions as such attorney-in-fact may approve in such attorney-in-fact's discretion.</div>
    <div><br>
    </div>
    <div style="text-align: justify;">I hereby grant to each attorney-in-fact hereunder full power and authority to do and perform any and every act and thing whatsoever necessary or desirable to be done in the exercise of any of the rights and powers
      herein granted, as fully to all intents and purposes as I might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact's substitute or
      substitutes, shall lawfully do or cause to be done by virtue of this Power of Attorney and the rights and powers herein granted.</div>
    <div><br>
    </div>
    <div style="text-align: justify;">I acknowledge that this Power of Attorney does not relieve me of my responsibilities to comply with Section 16 of the Act and the attorneys-in-fact, in serving in such capacity at my request, are not assuming, nor is
      the Company assuming, any of my responsibilities to comply with Section 16 of the Act.</div>
    <div><br>
    </div>
    <div style="text-align: justify;">This Power of Attorney shall remain in full force and effect until I am no longer required to file Section 16 Reports with respect to my holdings of and transactions in Company securities, unless I earlier revoke it in
      a signed writing delivered to the attorneys-in-fact.</div>
    <div><br>
    </div>
    <div style="text-align: justify;">IN WITNESS WHEREOF, I have caused this Power of Attorney to be executed as of this 17<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">th</sup> day of June, 2021.</div>
    <div><br>
    </div>
    <div style="text-align: justify;">By: <u>/s/ Pierre Caloz&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <br>
      </u></div>
    <div style="text-align: justify;">Print Name: Pierre Caloz<br>
    </div>
  </div>
</body>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
