    <SEC-DOCUMENT>0001104659-21-059264-index.html : 20210430
    <SEC-HEADER>0001104659-21-059264.hdr.sgml : 20210430
    <ACCEPTANCE-DATETIME>20210430172035
    ACCESSION NUMBER:		0001104659-21-059264
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		6
    CONFORMED PERIOD OF REPORT:	20210616
    FILED AS OF DATE:		20210430
    DATE AS OF CHANGE:		20210430

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			uniQure N.V.
    		CENTRAL INDEX KEY:			0001590560
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36294
    		FILM NUMBER:		21879901

    	BUSINESS ADDRESS:
    		STREET 1:		PAASHEUVELWEG 25A
    		CITY:			AMSTERDAM
    		STATE:			P7
    		ZIP:			1105 BP
    		BUSINESS PHONE:		1-339-970-7000

    	MAIL ADDRESS:
    		STREET 1:		PAASHEUVELWEG 25A
    		CITY:			AMSTERDAM
    		STATE:			P7
    		ZIP:			1105 BP

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	uniQure B.V.
    		DATE OF NAME CHANGE:	20131030
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>tm212677d2_def14a.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: tm212677d2_def14a.htm

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    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>tm212677d1_def14aimg001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: tm212677d1_def14aimg001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>tm212677d1_def14aimg002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: tm212677d1_def14aimg002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>tm212677d1_def14aimg003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: tm212677d1_def14aimg003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>tm212677d1_def14aimg005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: tm212677d1_def14aimg005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>tm212677d1_def14a-img02.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: tm212677d1_def14a-img02.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>