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Share-based compensation - Option activity and weighted-average assumptions (Details) - USD ($) $ / shares in Units, $ in Millions | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021
Share-based compensation |  |  |  |
Proceeds from options exercised |  |  | $ 0.5 |
Weighted average exercise price |  |  |  |
Total weighted average grant date fair value of options issued during the period (in $ millions) |  |  | 11.9 |
Proceeds from option sales during the period (in $ millions) |  |  | $ 0.5 |
2014 Plan |  |  |  |
Weighted average exercise price |  |  |  |
Vesting period (in years) |  |  | 4 years |
2014 Plan | Share options |  |  |  |
Options |  |  |  |
Outstanding at beginning of the period (in shares) |  |  | 3,308,325 |
Granted (in shares) |  |  | 1,343,496 |
Forfeited (in shares) |  |  | (106,166) |
Expired (in shares) |  |  | (66,587) |
Exercised (in shares) |  |  | (68,594) |
Outstanding at end of the period (in shares) | 4,410,474 |  | 4,410,474 |
Thereof, fully vested and exercisable at end of period (in shares) | 2,045,905 |  | 2,045,905 |
Thereof, outstanding and expected to vest at end of period (in shares) | 2,364,569 |  | 2,364,569 |
Weighted average exercise price |  |  |  |
Outstanding at beginning of the period (in dollars per share) |  |  | $ 31.02 |
Granted (in dollars per share) |  |  | 15.66 |
Forfeited (in dollars per share) |  |  | 37.70 |
Expired (in dollars per share) |  |  | 39.53 |
Exercised (in dollars per share) |  |  | 6.39 |
Outstanding at end of period (in dollars per share) | $ 26.44 |  | 26.44 |
Thereof, fully vested and exercisable at end of period (in dollars per share) | $ 27.21 |  | 27.21 |
Outstanding and expected to vest at end of the period (in dollars per share) |  |  | $ 25.77 |
Weighted-average assumptions used to estimate fair value of share options granted during year |  |  |  |
Expected volatility (as a percent) | 70.00% | 75.00% | 70.00% | 75.00%
Expected terms (in years) | 10 years | 10 years | 10 years | 10 years
Risk free interest rate, minimum (as a percent) | 3.03% | 1.72% | 2.12% | 1.21%
Risk free interest rate, maximum (as a percent) | 3.44% | 1.85% | 3.44% | 1.85%
Expected dividend (as a percent) | 0.00% | 0.00% | 0.00% | 0.00%
2014 Plan | Non-executive directors |  |  |  |
Weighted average exercise price |  |  |  |
Vesting period (in years) |  |  | 1 year |
2014 Plan | One year from grant date |  |  |  |
Weighted average exercise price |  |  |  |
Vesting percentage per year |  |  | 25.00% |
Vesting period (in years) |  |  | 1 year |

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- Definition The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(ii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.D.2) -URI http://asc.fasb.org/extlink&oid=122041274&loc=d3e301413-122809 + Details
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