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CSL Behring collaboration (Details) - USD ($) $ in Thousands		3 Months Ended			6 Months Ended
	Jun. 24, 2020	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Collaboration arrangements
Revenue		$ 497		$ 463,868	$ 2,289	$ 464,322
CSL Behring collaboration.
Collaboration arrangements
Upfront payment recorded	$ 450,000
Other payments received	$ 12,400
Accounts receivable		2,700			2,700		$ 2,900
Contract asset		55,000			55,000		$ 55,000
Inventory work in progress		2,000			2,000
Inventory raw materials		1,000			1,000
License revenues
Collaboration arrangements
Revenue				462,400		462,400
Collaborative revenue | CSL Behring collaboration.
Collaboration arrangements
Revenue				400	1,400	400
License revenue | CSL Behring collaboration.
Collaboration arrangements
Revenue		$ 0		$ 462,400	$ 0	$ 462,400

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