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Fair value measurement - BMS warrants - Narrative (Details) $ in Thousands		3 Months Ended		6 Months Ended
	Dec. 01, 2020 USD ($) item	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($)
Collaboration arrangements
Number of Collaboration Targets | item	4
Collaboration Agreement, Cash Payable	$ 70,000
Derivative gain (loss) on derivative net				$ 24,491	$ 12,279
Other nonoperating (losses) / gains
Collaboration arrangements
Derivative gain (loss) on derivative net		$ (100)	$ 0	600	$ 0
Non-current liabilities
Collaboration arrangements
Fair value of the derivative financial liability		$ 2,200		$ 2,200		$ 2,800
Collaboration Agreement, If 70 Million Is Greater Than Five Percent Of Net Proceeds | Derecognition Of Warrants
Collaboration arrangements
Threshold Percentage Of Net Proceeds	5.0
Percentage Of Net Proceeds Payable	5
Collaboration Agreement, If 70 Million Is Lesser Than One Percent Of Net Proceeds | Derecognition Of Warrants
Collaboration arrangements
Threshold Percentage Of Net Proceeds	1
Percentage Of Net Proceeds Payable	1

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- Definition

The amount of non-refundable, non-creditable cash payment to be made under the collaboration agreement.

+ References

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The percentage of net proceeds payable under the arrangement.

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The threshold percentage of net proceeds payable under the arrangement.

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Fair value, before effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes liabilities elected not to be offset. Excludes liabilities not subject to a master netting arrangement.

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Amount of increase (decrease) in the fair value of derivatives recognized in the income statement.

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