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Fair value measurement - Contingent Consideration (Details) $ in Thousands, € in Millions	6 Months Ended	12 Months Ended
	Jun. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)	Jun. 30, 2022 EUR (€)
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Contingent consideration, net of current portion	$ 20,405	$ 29,542
Contingent consideration	29,100
Current portion of contingent consideration	$ 8,681
One hundred percent likelihood of AMT-260 advancing into clinical development
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Percentage of increase in Probability of Success	100.00%
Change in fair value (presented within research and development expenses)	$ 46,100
Acquisition of Corlieve
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Contingent consideration, net of current portion	$ 29,086	$ 29,542
Percentage of increase in Probability of Success	55.00%	55.00%
Change in fair value (presented within research and development expenses)	$ 2,007
Currency translation effects	(2,463)
Acquisition of Corlieve | Maximum
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Contingent consideration payable upon achievement of contractually defined milestones	$ 186,900		€ 178.8
Contingent consideration discount rate percentage	11.70%	11.90%
Acquisition of Corlieve | Minimum
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Contingent consideration discount rate percentage	11.30%	10.90%

X

- Definition

The amount of contingent consideration payable upon achievement of contractually defined milestones.

+ References

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- Definition

The fair value of contingent consideration discount rate percentage.

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- Definition

Percentage of increase in Probability of Success in clinical development.

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- Definition

Amount of increase (decrease) in the value of a contingent consideration liability, including, but not limited to, differences arising upon settlement.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 28
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- Definition

Amount of liability recognized arising from contingent consideration in a business combination.

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Amount of liability recognized arising from contingent consideration in a business combination, expected to be settled beyond one year or the normal operating cycle, if longer.

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