XML 29 R14.htm IDEA: XBRL DOCUMENT
v3.22.4

Property, plant and equipment, net | 12 Months Ended
--- | ---
Dec. 31, 2022
Property, plant and equipment, net |
Property, plant and equipment, net | 8. Property, plant, and equipment, net ​ The following table presents the Company’s property, plant, and equipment as of December 31: ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31, | ​ | December 31,
​ |  | 2022 |  | 2021
​ | ​ | (in thousands)
Leasehold improvements | ​ | $ | 44,871 | ​ | $ | 45,372
Laboratory equipment | ​ | ​ | 39,393 | ​ | ​ | 25,499
Office equipment | ​ | ​ | 4,985 | ​ | ​ | 4,465
Construction-in-progress | ​ | ​ | 5,409 | ​ | ​ | 5,069
Total property, plant, and equipment | ​ | ​ | 94,658 | ​ | ​ | 80,405
Less accumulated depreciation | ​ | ​ | (44,126) | ​ | ​ | (36,900)
Property, plant and equipment, net | ​ | $ | 50,532 | ​ | $ | 43,505
​ Total depreciation expense was $8.2 million for the year ended December 31, 2022 (December 31, 2021: $6.1 million, December 31, 2020: $5.7 million). Depreciation expense is allocated to research and development expenses and cost of contract manufacturing to the extent it relates to the Company’s manufacturing facility and equipment and laboratory equipment. All other depreciation expenses are allocated to selling, general and administrative expense. ​ The following table summarizes property, plant, and equipment by geographic region. ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | December 31, |  | December 31,
​ | ​ | 2022 | ​ | 2021
​ | ​ | (in thousands)
Lexington, Massachusetts (United States of America) | ​ | $ | 20,258 | ​ | $ | 17,311
Amsterdam (the Netherlands) | ​ |  | 30,252 | ​ |  | 26,160
Other | ​ | ​ | 22 | ​ | ​ | 34
Total | ​ | $ | 50,532 | ​ | $ | 43,505
​

X
- References No definition available. + Details
Name: | us-gaap_PropertyPlantAndEquipmentAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 6 -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99893-112916 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -URI https://asc.fasb.org/topic&trid=2155823 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 7 -URI https://asc.fasb.org/extlink&oid=126982197&loc=SL120174063-112916 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 1 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99779-112916 + Details
Name: | us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration