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Collaboration arrangements and concentration of credit risk - Amounts owed by BMS (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total revenues | $ 106,483 | $ 524,002 | $ 37,514
BMS arrangement |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Amounts owed in relation to the collaboration services | 136 | 914 |
Total revenues | 1,752 | 4,176 | 37,514
BMS arrangement | Bristol Myers Squibb |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Amounts owed in relation to the collaboration services | 136 | 914 |
Total revenues | $ 1,752 | $ 4,176 | $ 37,514

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