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Fair value measurement and Other non-operating (losses) / gains - BMS warrants (Details) $ in Thousands |  | 12 Months Ended |
--- | --- | --- | ---
Dec. 01, 2020 USD ($) item | Dec. 31, 2022 USD ($) item | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($)
Collaboration arrangements |  |  |  |  |
Number of warrant types |  | 2 |  |  |
Number of collaboration targets | 4 |  |  |  |
Collaboration agreement, cash payable | $ | $ 70,000 |  |  |  |
Fair value of derivative financial instruments | $ |  | $ 35,316 | $ 32,347 | $ 2,645 | $ 3,075
Fair value of the derivative financial liability | $ |  | 0 |  |  |
CoC-payment |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Gain (Loss) from the recognition of the derivative financial liability | $ |  |  | (200) | (2,600) |
Other nonoperating (losses) / gains | CoC-payment |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Gain (Loss) from the recognition of the derivative financial liability | $ |  | $ 2,800 |  |  |
Non-current liabilities |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Fair value of the derivative financial liability | $ |  |  | $ 2,800 |  |
BMS arrangement |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Number of collaboration targets |  | 4 |  |  |
BMS arrangement | Bristol Myers Squibb |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Number of collaboration targets |  | 4 |  |  |
BMS arrangement | Bristol Myers Squibb | Maximum |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Number of collaboration targets | 4 |  |  |  |
BMS Warrants | Fair value hierarchy Level 3 |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Gain (Loss) recorded due to changes in fair value of derivative asset | $ |  |  |  | $ 3,100 |
Fair Value, Asset, Recurring Basis, Unobservable Input Reconciliation, Gain (Loss), Statement of Income or Comprehensive Income [Extensible Enumeration] |  |  |  | Other Nonoperating Income (Expense). |
BMS Warrants | BMS arrangement |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Gain (Loss) recorded due to changes in fair value of derivative asset | $ |  |  |  | $ 800 |
Collaboration Agreement, If 70 Million Is Greater Than Five Percent Of Net Proceeds | Derecognition Of Warrants |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Threshold percentage of net proceeds | 5.0 |  |  |  |
Percentage Of net proceeds payable | 5 |  |  |  |
Collaboration Agreement, If 70 Million Is Lesser Than One Percent Of Net Proceeds | Derecognition Of Warrants |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Threshold percentage of net proceeds | 1 |  |  |  |
Percentage Of net proceeds payable | 1 |  |  |  |
Bristol Myers Squibb | uniQure N.V. | First Six New Targets Or Designation Of Sixth Target | BMS Warrants |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Ownership percentage required per agreement |  | 14.90% |  |  |
Bristol Myers Squibb | uniQure N.V. | First Six New Targets Or Designation Of Sixth Target | BMS Warrants | Minimum |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Number of collaboration targets |  | 6 |  |  |
Bristol Myers Squibb | uniQure N.V. | First Six New Targets Or Designation Of Sixth Target | BMS Warrants | Maximum |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Number of collaboration targets |  | 7 |  |  |
Bristol Myers Squibb | uniQure N.V. | First Nine New Targets Or Designation Of Ninth Target | BMS Warrants |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Ownership percentage required per agreement |  | 19.90% |  |  |
Bristol Myers Squibb | uniQure N.V. | First Nine New Targets Or Designation Of Ninth Target | BMS Warrants | Minimum |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Number of collaboration targets |  | 9 |  |  |
Bristol Myers Squibb | uniQure N.V. | First Nine New Targets Or Designation Of Ninth Target | BMS Warrants | Maximum |  |  |  |  |
Collaboration arrangements |  |  |  |  |
Number of collaboration targets |  | 10 |  |  |

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