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v3.22.4

Shareholder's equity (Details) € / shares in Units, $ / shares in Units, € in Millions |  | 2 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Mar. 01, 2021 USD ($) | Apr. 30, 2021 USD ($) $ / shares shares | Dec. 31, 2022 USD ($) $ / € shares | Dec. 31, 2021 USD ($) | Dec. 31, 2022 EUR (€) € / shares $ / € shares | Dec. 31, 2021 € / shares | Dec. 31, 2021 USD ($) shares | Jun. 16, 2021 shares | Dec. 31, 2020 USD ($)
Authorized share capital |  |  | $ 4,300,000 |  | € 4.0 |  |  |  |
Common stock, additional shares authorized | shares |  |  |  |  |  |  |  | 20,000,000 |
Exchange rate (in USD per Euro) | $ / € |  |  | 1.07 |  | 1.07 |  |  |  |
Ordinary shares, authorized | shares |  |  | 80,000,000 |  | 80,000,000 |  | 80,000,000 |  |
Ordinary shares, par value (in euros per share) | € / shares |  |  |  |  | € 0.05 | € 0.05 |  |  |
Accumulated other comprehensive loss |  |  | $ (58,291,000) |  |  |  | $ (28,856,000) |  | $ (9,900,000)
Aggregate offering price |  |  |  | $ 29,564,000 |  |  |  |  |
Income tax benefit of past share issuance cost |  |  | 808,000 | 3,047,000 |  |  |  |  |
Increase of additional paid in capital |  |  | 800,000 |  |  |  |  |  |
Sales Agreement with SVB Leerink LLC |  |  |  |  |  |  |  |  |
Percentage of gross proceeds | 3.00% |  |  |  |  |  |  |  |
Sales Agreement with SVB Leerink LLC | Direct Incremental Labor |  |  |  |  |  |  |  |  |
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs |  |  | $ 0 | $ 1,300,000 |  |  |  |  |
Sales Agreement with SVB Leerink LLC | Ordinary shares |  |  |  |  |  |  |  |  |
Shares issued in connection with offering | shares |  | 921,730 |  |  |  |  |  |  |
Share price (in dollars per share) | $ / shares |  | $ 33.52 |  |  |  |  |  |  |
Net proceeds |  | $ 29,600,000 |  |  |  |  |  |  |
Sales Agreement with SVB Leerink LLC | Maximum |  |  |  |  |  |  |  |  |
Aggregate offering price | $ 200,000,000.0 |  |  |  |  |  |  |  |

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