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Property, plant and equipment, net

12 Months Ended

Dec. 31, 2022

Property, plant and equipment, net

Property, plant and equipment, net

8.         Property, plant, and equipment, net

​

The following table presents the Company’s property, plant, and equipment as of December 31:

​

​	​	​	​	​	​	​
​	​	December 31,		​	December 31,
​		2022			2021
​	​	(in thousands)
Leasehold improvements	​	$	44,871	​	$	45,372
Laboratory equipment	​	​	39,393	​	​	25,499
Office equipment	​	​	4,985	​	​	4,465
Construction-in-progress	​	​	5,409	​	​	5,069
Total property, plant, and equipment	​	​	94,658	​	​	80,405
Less accumulated depreciation	​	​	(44,126)	​	​	(36,900)
Property, plant and equipment, net	​	$	50,532	​	$	43,505

​

Total depreciation expense was $8.2 million for the year ended December 31, 2022 (December 31, 2021: $6.1 million, December 31, 2020: $5.7 million). Depreciation expense is allocated to research and development expenses and cost of contract manufacturing to the extent it relates to the Company’s manufacturing facility and equipment and laboratory equipment. All other depreciation expenses are allocated to selling, general and administrative expense.

​

The following table summarizes property, plant, and equipment by geographic region.

​

​	​	​	​	​	​	​
​		December 31,			December 31,
​	​	2022		​	2021
​	​	(in thousands)
Lexington, Massachusetts (United States of America)	​	$	20,258	​	$	17,311
Amsterdam (the Netherlands)	​		30,252	​		26,160
Other	​	​	22	​	​	34
Total	​	$	50,532	​	$	43,505

​

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- References

No definition available.

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- Definition

The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 958
-SubTopic 360
-Section 50
-Paragraph 6
-URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99893-112916

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-URI https://asc.fasb.org/topic&trid=2155823

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 958
-SubTopic 360
-Section 50
-Paragraph 7
-URI https://asc.fasb.org/extlink&oid=126982197&loc=SL120174063-112916

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 958
-SubTopic 360
-Section 50
-Paragraph 1
-Subparagraph (d)
-URI https://asc.fasb.org/extlink&oid=126982197&loc=d3e99779-112916

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