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Property, plant and equipment, net (Tables)
12 Months Ended
Dec. 31, 2022
Property, plant and equipment, net  
Schedule of property, plant and equipment

December 31, 

December 31, 

    

2022

    

2021

(in thousands)

Leasehold improvements

$

44,871

$

45,372

Laboratory equipment

39,393

25,499

Office equipment

4,985

4,465

Construction-in-progress

5,409

5,069

Total property, plant, and equipment

94,658

80,405

Less accumulated depreciation

(44,126)

(36,900)

Property, plant and equipment, net

$

50,532

$

43,505

Summary of long-lived assets by geographic region

    

December 31, 

    

December 31, 

2022

2021

(in thousands)

Lexington, Massachusetts (United States of America)

$

20,258

$

17,311

Amsterdam (the Netherlands)

 

30,252

 

26,160

Other

22

34

Total

$

50,532

$

43,505