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Collaboration arrangements and concentration of credit risk - Amounts owed by BMS (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Total revenues	$ 106,483	$ 524,002	$ 37,514
BMS arrangement
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Amounts owed in relation to the collaboration services	136	914
Total revenues	1,752	4,176	37,514
BMS arrangement | Bristol Myers Squibb
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Amounts owed in relation to the collaboration services	136	914
Total revenues	$ 1,752	$ 4,176	$ 37,514

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