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Long-term debt (Details) - USD ($) $ in Thousands					12 Months Ended
Long-term debt (Details) - USD ($) $ in Thousands	Apr. 01, 2024	Dec. 15, 2021	Jan. 29, 2021	Dec. 06, 2018	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	May 31, 2020
Aggregate maturities of loan
Coupon interest payments and financing fees					$ 44,500
2023					14,870
2024					12,403
2025					117,219
Total					144,492
Prime Rate
Long-term Debt
Variable interest rate basis			8.25%
2016 Amended Facility \| Hercules \| Second Amended and Restated Loan and Security Agreement [Member]
Long-term Debt
Outstanding debt				$ 20,000
Proceed from drew down				$ 15,000
Interest rate (as a percent)				8.85%
Back-end fees due								$ 1,000
2016 Amended Facility \| Prime Rate \| Hercules \| Second Amended and Restated Loan and Security Agreement [Member]
Long-term Debt
Variable interest rate basis				8.85%
Discount rate (as a percent)				5.50%
2018 Amended Facility
Long-term Debt
Amortized cost net of discount and debt issuance costs						$ 101,600
2021 Amended Facility
Long-term Debt
Outstanding debt			$ 35,000
Proceed from drew down			$ 35,000
Interest rate (as a percent)			8.25%
Maximum borrowing capacity			$ 135,000
Additional unconditional borrowing capacity			$ 100,000
2021 Amended Facility \| Minimum
Long-term Debt
Back-end fee (as a percent)			1.65%
2021 Amended Facility \| Maximum
Long-term Debt
Back-end fee (as a percent)			6.85%
2021 Amended Facility \| Prime Rate
Long-term Debt
Discount rate (as a percent)			3.25%
2018 and 2021 Amended Facility
Long-term Debt
Outstanding debt		$ 70,000	$ 70,000
Foreign currency loss					5,800		$ 3,100
Foreign currency gain						5,300
Restated Facility 2021
Long-term Debt
Outstanding debt		100,000				100,000
Proceed from drew down		$ 30,000
Interest rate (as a percent)		7.95%
Back-end fees due		$ 4,850			2,500
Amortized cost net of discount and debt issuance costs					103,800
Restated Facility 2021 \| Prime Rate
Long-term Debt
Variable interest rate basis		7.95%
Discount rate (as a percent)		3.25%
Venture debt loan facility \| 2018 and 2021 Amended Facility \| Hercules
Long-term Debt
Interest expense recorded					$ 11,500	$ 7,200	$ 3,700
Venture debt loan facility \| Restated Facility 2021
Long-term Debt
Minimum cash and cash equivalents in U.S. bank accounts					65.00%	100.00%
Assets pledged to secure facilities by directly or indirectly					$ 705,000
Assets not being pledged to secure facilities by directly or indirectly					63,700
Venture debt loan facility \| Restated Facility 2021 \| Corlieve Therapeutics SAS
Long-term Debt
Assets not being pledged to secure facilities by directly or indirectly					$ 85,200
Subsequent events. \| Venture debt loan facility \| Restated Facility 2021
Long-term Debt
Minimum cash and cash equivalents in U.S. bank accounts	30.00%