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Income taxes - Changes in valuation allowance (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Opening balance	$ 60,289	$ 150,113	$ 109,856
Changes recorded in the statement of operations	20,593	(88,858)	30,568
Changes recorded in equity	(972)
Increase related to 2021 and 2020 Dutch tax reforms		1,897	18,287
Valuation allowance assumed in Corlieve acquisition		545
Other changes including currency translation adjustments	(5,363)	(3,408)	7,821
Ending balance	74,547	60,289	150,113
Amount of valuation allowance for deferred tax assets within contributed capital as it relates to follow on offering costs.	$ 3,300	$ 4,500
U.S. operations
Changes recorded in the statement of operations			(16,419)
Release of valuation allowance related to expected current year and future periods recorded in profit and loss			$ (16,419)

X

- Definition

Release of valuation allowance related to current year and future periods recorded in profit and loss.

+ References

No definition available.

+ Details

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X

- Definition

Amount of valuation allowance deferred tax asset changes recorded in equity.

+ References

No definition available.

+ Details

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- Definition

Valuation Allowance, Deferred Tax Asset, Changes Recorded in Profit and Loss

+ References

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- Definition

Valuation Allowance, Deferred Tax Asset, Changes Recorded in Profit and Loss Related to Tax Reform

+ References

No definition available.

+ Details

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- Definition

Valuation Allowance, Deferred Tax Asset, Currency Translation Effects

+ References

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- Definition

Amount of valuation allowance deferred tax asset on acquisition.

+ References

No definition available.

+ Details

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X

- Definition

Amount of valuation allowance for deferred tax assets within contributed capital as it relates to follow on offering costs.

+ References

No definition available.

+ Details

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X

- Definition

Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)
-URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319

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