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Share-based compensation (Tables) | 3 Months Ended
--- | ---
Mar. 31, 2024
Share-based compensation |
Schedule of share-based compensation expense by classification included in consolidated statements of operations and comprehensive loss | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
| ​ | Three months ended March 31,
​ | ​ | 2024 | ​ | 2023
​ | ​ | (in thousands)
Cost of manufacturing services revenue | ​ | $ | 345 | ​ | $ | 24
Research and development | ​ | ​ | 3,425 | ​ | ​ | 4,305
Selling, general and administrative | ​ | ​ | 3,421 | ​ | ​ | 3,732
Total | ​ | $ | 7,191 | ​ | $ | 8,061
Schedule of share-based compensation expense | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three months ended March 31,
​ | ​ | 2024 | ​ | 2023
​ | ​ | (in thousands)
Award type/ESPP | ​ | ​ | ​ | ​ | ​ | ​
Share options | ​ | $ | 2,913 | ​ | $ | 3,274
Restricted share units | ​ | ​ | 4,370 | ​ | ​ | 4,630
Performance share units | ​ | ​ | (99) | ​ | ​ | 150
Employee share purchase plan | ​ | ​ | 7 | ​ | ​ | 7
Total | ​ | $ | 7,191 | ​ | $ | 8,061
Schedule of unrecognized compensation cost related to unvested awards | ​
​ | ​ | ​ | ​ | ​ | ​
​ |  | Unrecognized |  | Weighted average
​ |  | share-based |  | remaining
​ | ​ | compensation | ​ | period for
​ | ​ | expense | ​ | recognition
​ | ​ | (in thousands) | ​ | (in years)
Award type | ​ | ​ | ​ | ​ | ​
Share options | ​ | $ | 20,743 | ​ | 2.56
Restricted share units | ​ | ​ | 27,981 | ​ | 1.99
Performance share units | ​ | ​ | 80 | ​ | 0.61
Total | ​ | $ | 48,804 | ​ | 2.23
Schedule of weighted-average assumptions for fair value of option issued | ​
​ | ​ | ​ | ​ | ​
​ | ​ | Three months ended March 31,
Assumptions |  | 2024 |  | 2023
Expected volatility | ​ | 70% | ​ | 70%
Expected terms | ​ | 10 years | ​ | 10 years
Risk free interest rate | ​ | 4.32% | ​ | 4.10%
Expected dividend yield | ​ | 0% | ​ | 0%
Summary of RSUs activity | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | RSUs
​ |  | ​ |  | Weighted average
​ | ​ | Number of | ​ | grant-date fair
​ | ​ | ordinary shares | ​ | value
Non-vested at December 31, 2023 | ​ | 2,264,369 | ​ | $ | 18.07
Granted | ​ | 1,160,800 | ​ | $ | 5.59
Vested | ​ | (659,240) | ​ | $ | 20.30
Forfeited | ​ | (58,401) | ​ | $ | 17.39
Non-vested at March 31, 2024 | ​ | 2,707,528 | ​ | $ | 12.19
​ | ​ | ​ | ​ | ​ | ​
Total weighted average grant date fair value of RSUs granted during the period (in $ millions) | ​ | ​ | ​ | $ | 6.5
Summary of PSUs activity | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | PSUs
​ |  | ​ |  | Weighted average
​ | ​ | Number of | ​ | grant-date fair
​ | ​ | ordinary shares | ​ | value
Non-vested at December 31, 2023 | ​ | 222,550 | ​ | $ | 28.09
Forfeited | ​ | (17,030) | ​ | $ | 27.12
Non-vested at March 31, 2024 | ​ | 205,520 | ​ | $ | 27.99
2014 Plan |
Share-based compensation |
Summary of option activity | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Options
​ | ​ | Number of | ​ | Weighted average
​ |  | ordinary shares |  | exercise price
​ | ​ | ​ | ​ | ​ | ​
Outstanding at December 31, 2023 | ​ | 4,974,030 | ​ | ​ | 23.25
Granted | ​ | 930,900 | ​ | $ | 5.59
Forfeited | ​ | (71,437) | ​ | $ | 21.26
Expired | ​ | (11,584) | ​ | $ | 37.61
Outstanding at March 31, 2024 | ​ | 5,821,909 | ​ | $ | 20.42
Thereof, fully vested, and exercisable on March 31, 2024 | ​ | 3,054,242 | ​ | $ | 25.70
Thereof, outstanding and expected to vest after March 31, 2024 | ​ | 2,767,667 | ​ | $ | 14.60
Outstanding and expected to vest after December 31, 2023 | ​ | 2,098,557 | ​ | $ | 23.38
​ | ​ | ​ | ​ | ​ | ​
​
​ | ​ | ​ | ​ | ​ | ​
Total weighted average grant date fair value of options issued during the period (in $ millions) | ​ | ​ | ​ | $ | 3.0
​

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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